• 3 years ago
Zinc and immune function: the biological basis of altered resistance to infection
Zinc is known to play a central role in the immune system

and zinc-deficient persons experience increased susceptibility to a variety of pathogens

It is clear that zinc affects multiple aspects of the immune system

Zinc is crucial for normal development and function of cells mediating nonspecific immunity such as neutrophils and natural killer cells

Zinc deficiency also affects development of acquired immunity, activation of T lymphocytes and B lymphocyte help

B lymphocyte development and antibody production, particularly immunoglobulin G, is compromised

The macrophage, is adversely affected by zinc deficiency

Zinc is needed by these key immunologic mediators

Basic cellular functions such as DNA replication
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