• 4 months ago
Discover the groundbreaking mRNA therapy that’s giving new hope to cancer patients in the UK! Join us as we explore how this cutting-edge treatment is helping the body’s immune system recognize and fight cancer cells. Hear from the experts and the first UK patient to receive this revolutionary therapy. Don't miss this incredible story of innovation and hope!
Location: London, UK
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00:00Today, we bring you an incredible breakthrough in cancer treatment.
00:03The first UK patients are now receiving an experimental mRNA therapy for cancer.
00:08Introducing mRNA, 4359, a cutting-edge immunotherapy.
00:13This revolutionary treatment aims to train the immune system to recognize and attack
00:17cancer cells.
00:19The therapy uses messenger RNA to present common markers of tumors, helping the body's
00:23immune system identify and fight cancer more effectively.
00:27This treatment is part of a global phase half-clinical trial happening right here at
00:31Imperial College Healthcare NHS Trust.
00:33Dr. Nikola Awosika, member of the clinical research delivery team that delivered the
00:38first dose of mRNA-4359 in the UK, said,
00:43It's exciting to contribute to innovative treatments like this.
00:47We are grateful for our patients' participation.
00:50The trial is a collaboration between Imperial College London and Imperial College Healthcare
00:55NHS Trust.
00:56It aims to treat melanoma, lung cancer, and other solid tumors.
01:01Patients are receiving mRNA-4359 alone, or combined with pembrolizumab, an existing cancer
01:07drug, to test safety and effectiveness.
01:10Dr. David Panotto, a clinician scientist at Imperial College London's Department of Surgery
01:15in Cancer and consultant medical oncologist at Imperial College Healthcare NHS Trust,
01:20said,
01:21New mRNA therapies offer a new avenue for recruiting the patient's own immune system
01:26to fight cancer.
01:27We're laying crucial groundwork for future treatments.
01:30An 81-year-old man with treatment-resistant melanoma was the first to receive this therapy.
01:36He expressed relief and hope, knowing he's contributing to a potential game-changer.
01:40Nearly one in two people in the UK will face cancer.
01:44Traditional treatments sometimes fail, but this new mRNA therapy offers hope for more
01:49effective, less toxic options.
01:51Secretary of State for Health and Social Care, Victoria Atkins, said,
01:56Cancer can affect any of us, be it through devastating diagnosis, the difficulties faced
02:01during treatment, or the loss of a loved one.
02:04But huge progress is being made, and survival rates are at an all-time high.
02:08Join us in supporting this groundbreaking trial.
02:11Share this video and comment below with your thoughts.
02:14Together, we can turn the tide against cancer.

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