The C-Reactive Protein (CRP) test measures the level of CRP in the blood, a protein produced by the liver in response to inflammation. Elevated CRP levels indicate acute or chronic inflammation, which can result from infections, injuries, autoimmune disorders, or chronic diseases like cardiovascular disease (CVD).
There are two main types of CRP tests:
Standard CRP Test – Detects general inflammation, useful for monitoring infections or autoimmune diseases like rheumatoid arthritis.
High-Sensitivity CRP (hs-CRP) Test – Measures very low CRP levels to assess heart disease risk, as chronic low-grade inflammation is linked to atherosclerosis.
A high CRP level does not diagnose a specific condition but signals the need for further testing. For CVD risk assessment, an hs-CRP level below 1 mg/L indicates low risk, 1-3 mg/L moderate risk, and above 3 mg/L high risk.
Factors like smoking, obesity, and lack of exercise can increase CRP levels. The test requires a simple blood draw and no fasting. While useful, results should be interpreted alongside other tests since CRP can rise due to temporary conditions like infections. Managing inflammation through a healthy lifestyle, medications, or treating underlying conditions can help lower CRP levels and reduce disease risks.
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There are two main types of CRP tests:
Standard CRP Test – Detects general inflammation, useful for monitoring infections or autoimmune diseases like rheumatoid arthritis.
High-Sensitivity CRP (hs-CRP) Test – Measures very low CRP levels to assess heart disease risk, as chronic low-grade inflammation is linked to atherosclerosis.
A high CRP level does not diagnose a specific condition but signals the need for further testing. For CVD risk assessment, an hs-CRP level below 1 mg/L indicates low risk, 1-3 mg/L moderate risk, and above 3 mg/L high risk.
Factors like smoking, obesity, and lack of exercise can increase CRP levels. The test requires a simple blood draw and no fasting. While useful, results should be interpreted alongside other tests since CRP can rise due to temporary conditions like infections. Managing inflammation through a healthy lifestyle, medications, or treating underlying conditions can help lower CRP levels and reduce disease risks.
Don’t forget to like, comment, and subscribe for more health-focused content!
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LearningTranscript
00:00C-reactive protein is an acute phase protein produced by the liver in response to inflammation,
00:06especially due to interleukin-6 produced by macrophages and T-cells. CRP levels rise rapidly
00:13after tissue injury, infection, or other inflammatory stimuli, making it a sensitive
00:18marker for systemic inflammation. CRP is indicated for various clinical conditions,
00:24including the following. Infection and sepsis. Autoimmune diseases such as rheumatoid arthritis,
00:31systemic lupus erythematosus, and inflammatory bowel disease to monitor disease activity.
00:38Cardiovascular risk assessment. High-sensitivity CRP is used to assess the risk of myocardial
00:44infarction and stroke. In post-operative monitoring to detect potential complications like infection,
00:50and for monitoring response to therapy in conditions like infection and inflammatory
00:56diseases. CRP levels can be measured quantitatively using methods such as immunoturbidimetry,
01:02nephilometry, and enzyme-linked immunosorbinase, or ELISA. These methods are based on antigen
01:09antibody reactions, where anti-CRP antibodies bind to CRP in the sample, forming immune complexes.
01:16The degree of turbidity or light scatter correlates with CRP concentration. If the CRP concentration
01:23is less than 10 mg per liter, it indicates low or absent inflammation or infection. If the CRP
01:30concentration is more than 10 mg per liter, it indicates the presence of infection or inflammation.
01:37A CRP concentration more than 100 mg per liter is suggestive of significant infection or inflammation.
01:44In viral infections, the CRP level is usually between 20 to 40, whereas in bacterial infections,
01:51it often exceeds 100. It is important to note that the CRP test is nonspecific,
01:57and it doesn't indicate the exact cause or location of inflammation. In addition, it may be elevated in
02:03conditions like trauma, surgery, malignancy, or obesity. Therefore, it should be interpreted in
02:10clinical context and often alongside ESR, complete blood count, and other relevant tests.
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02:24These genes may not be Office of the naturalcs, but it doesn't indicate the
02:27Compassion of the technology. If it comes to your channel, you may not have access to
02:31or the value of the solution. This is a basic repair that is all of the information,
02:37which is one of the sources of the schools of the state of law or state and the