• 10 months ago
Elon Musk’s brain implant company Neuralink says it's first human patient is recovering after being implanted with a device which helps them communicate through a phone or computers.

According to Musk’s social media messages the first patients being fitted with the implant will be those who’ve lost use of their limbs.

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00:00 Your brain sends neural signals and their electrical signals go from one brain cell,
00:05 one neuron to another.
00:07 And when those signals are transmitted, you can record the electrical activity.
00:11 You can record it very precisely with electrodes that you implant in the brain, like these
00:15 brain computer interfaces, or you can get sort of an aggregate of the brain signals
00:19 by taking a surface recording.
00:22 And what that does normally is those electrical signals, for example, from your motor cortex,
00:26 will travel down to your spinal cord and send that signal to a motor neuron in your spinal
00:31 cord and that flexes your muscle.
00:32 Your brain has 100 billion of these neurons all talking to each other and firing, and
00:37 you have developed this phenomenally complex nervous system and evolved it to work.
00:42 But what we have to do when you're just getting little signals, just like a little spike from
00:47 these neurons, is the computer has to interpret what that means.
00:50 So you have to train the computer to say, "When I am moving my left foot or thinking
00:54 about moving my left foot, this is what those signals look like."
00:58 What a spike is and what electrophysiologists and neuroscientists call spikes are when a
01:03 neuron fires.
01:04 So your neurons in your brain are receiving signals from other cells all the time, and
01:08 if they get a strong enough signal, they send an action potential, which we call a spike,
01:13 and that sends a signal down a long wire to a different neuron.
01:16 And so that's an electrical signal that you can measure.
01:19 So these devices are just hearing that electrical signal, that one big spike, and what you can
01:24 do then, that's an electrical signal that's almost like if you're pushing a button on
01:27 your computer.
01:28 Every time you heard a beep, if you pushed a button on your computer, you could cause
01:31 your computer to do something.
01:33 So the part from the signal being interpreted by the brain-computer interface and how it
01:39 influences something outside of your body is a lot like a Wi-Fi signal.
01:43 So I think Neuralink says they have no wires, so I assume it's a wireless signal.
01:47 So they'll take those electrical signals, the computer will decode them and say, "This
01:51 person is thinking about moving the mouse to the right."
01:54 That electrical signal then goes, it's just like putting a robot and moving your mouse
01:58 to the right.
01:59 So it's just an electrical impulse, the way we would program a computer or a robot to
02:03 do anything.
02:04 The complex bit is interpreting the brain signal so that you can tell that robot or
02:09 that machine what to do.
02:11 There was a fascinating case published last year in Switzerland, a man who was completely
02:15 paralyzed and had one of these early brain-computer interfaces experimentally implanted in his
02:20 brain, recording from the part of the brain that controls movement.
02:24 And then a very advanced machine learning, so artificial intelligence algorithm, interpreted
02:28 those signals and sent them directly to his spinal cord below where the injury was so
02:32 he could walk.
02:33 So this is how amazing neuroscience is that even in, only in trials so far, but you can
02:38 actually decode what the brain is saying now and use that to generate movement.
02:42 This is a similar principle to Neuralink, these ideas that you can help people speak.
02:47 I've seen several studies, some of which use non-invasive methods like scalp electrodes
02:52 to record brain activity or functional MRI, so a brain scan essentially.
02:57 And that's a little bit less precise than sticking an electrode directly into your brain
03:01 and recording a signal.
03:02 But what it is allowing people to do in collaboration with these hugely powerful computer systems
03:08 is for people to think about words and those to be interpreted by the computer.
03:12 And then, you know, you could use that to type or to generate speech.
03:15 So this is research that's coming along and it's fascinating.
03:19 It's not in the studies I've read, perfect by any means.
03:22 So one of the studies I read could only accurately interpret 50% of the words someone was thinking.
03:27 So it's not perfect yet, but it's part of the direction the field is going.
03:32 So just this idea that understanding the brain and neuroscience and bringing that together
03:36 with artificial intelligence and computers is really going to, I think, start making
03:40 a difference in people's lives, both, as you say, in moving if you've had an injury and
03:46 in speaking if you can't speak for some reason, like a stroke or things like that.
03:50 I have heard that they're recruiting people who have ALS, amyotrophic lateral sclerosis,
03:56 or some types of paralysis.
03:57 So I'm guessing that in the future, they won't just be using the Neuralink to tell your phone
04:03 what to do or to move a cursor on a computer screen or play a game, but to actually send
04:07 the signals to a robot or send the signals to a prosthetic limb, for example, or even
04:11 if they follow what this group in Switzerland did, you could directly stimulate the spinal
04:15 cord if that's intact.
04:17 Clinicians who work in Parkinson's disease have been able to treat Parkinson's symptoms
04:21 by directly stimulating the brain, and that stops some of the motor symptoms.
04:25 So as you know, in Parkinson's, you have a tremor sometimes, trouble initiating movement,
04:29 and by directly stimulating part of the brain with electrodes that are quite similar to
04:33 the brain-computer interfaces,
04:34 you can alleviate some of the symptoms.

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