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From heartwarming moments to hilarious interactions, join us as we count down the best Sheldon and Mary Cooper scenes across both The Big Bang Theory and Young Sheldon! Whether it's Mary's clever problem-solving or Sheldon's unique way of showing affection, these moments showcase the special bond between this iconic mother-son duo.

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00:00Mom is here to take care of her baby.
00:02Just to be clear, only her baby.
00:06Welcome to Ms. Mojo, and today we're looking at the times when Sheldon and Mary Cooper's relationship melted the fanbase's heart.
00:13Look out for some minor spoilers.
00:15Happy kitty, sleepy kitty, purr, purr, purr.
00:22Number 10. Mary gets Sheldon his job back.
00:25After landing in hot water for insulting his boss, Dr. Gabelhauser, the unemployed Sheldon starts getting on everyone's nerves.
00:32One of the great minds of the 21st century is raising glow-in-the-dark fish and weaving syrupees.
00:39This is not a syrupee. This is a poncho. A syrupee is open at the sides. A poncho is closed. This is a poncho.
00:45And neither is a reason to call someone's mother.
00:48With no other solution, everyone turns to Mary to fix this problem.
00:52Fans get their first look into how Sheldon's mom understands her eccentric son, and it's like watching a master at work.
00:59It's okay to be smarter than everybody, but you can't go around pointing it out.
01:03Why not?
01:04Because people don't like it.
01:07Remember all the ass-kickings you got from the neighbor kids?
01:13Now let's get cracking. Shower, shirt, shoes, and let's shove off.
01:19She does one better with Dr. Gabelhauser, using her natural charm and quick wit to gain the latter's favor.
01:26Sheldon cluelessly witnessing the duo's flirtation is always hilarious to watch, failing to realize how his mother gets him his job back.
01:34Right from her first on-screen appearance, Mary proves why no one else can handle Sheldon like she can.
01:40You must have had him when you were a teenager.
01:42Oh, aren't you sweet? His father's dead.
01:46Recently?
01:47Long enough.
01:49Please.
01:52Sheldon, shouldn't you be working?
01:58Okay.
02:009. Sheldon spites Mary
02:03Let's be honest, nobody thought Sheldon would ever find a romantic partner, let alone get married, so it's easy to see why his own mother had the same reservations.
02:12By your third birthday, you had memorized over a thousand different kinds of trains, and I never imagined a woman getting aboard any of them.
02:24Most of us would probably be a bit more tactful when admitting this, but Mary takes a hilariously blunt approach.
02:30Naturally, the ever-sensitive Sheldon takes offense, responding how he does best, with spiteful vengeance.
02:37Upset about being called immature, he throws a childish tantrum, ironically proving his mom right.
02:43Sheldon's meltdown is funny, but Mary's casual nonchalance is arguably funnier.
02:53As expected, his antics only harm him more than her, making all of it a giant waste of time.
02:59Classic Sheldon.
03:08AHHHHH!
03:11And here we are.
03:138. Mary and Sheldon in Germany
03:16We won't forget how Mary stole Sheldon's thunder on his first day of college anytime soon.
03:21As memorable as that is, the mother-son duo has another college adventure abroad.
03:26Sheldon certainly puts Mary through a lot, from testing her patience on the plane to getting lost in Germany.
03:32When I was leaving the library, a wild dog attacked me.
03:37Oh, sweetie, no.
03:38I fought him off, but at the price of a loafer.
03:41Where's your backpack?
03:44I guess he got that, too.
03:46The tables turn when his mother behaves out of character.
03:49Experiencing culture shock and feeling homesick, Mary chugs down a bit more than she should.
03:55Thank you for all the joy and pain.
04:01Picture shows, second balcony.
04:05It doesn't matter how smart or unique you are.
04:08Getting embarrassed by your parents is a universal absolute.
04:12Too bad this is when Sheldon feels the brunt of it.
04:15Flipping their usual dynamic on its head, it's a reminder that with these two, laughter is guaranteed.
04:21Sing it with me!
04:22Dunk of shame, darling, dunk of shame.
04:26I don't know what could have gotten into her.
04:29Probably jet lag.
04:317. Sheldon thanks Mary
04:33He may be more than a handful, but Sheldon will always be Mary's precious baby.
04:39I wish your dad could see you now.
04:41Me too.
04:43I miss him.
04:45He would be so proud of you.
04:47I know that I am.
04:50While Sheldon usually takes more love than he gives, the character holds his mother in high regard.
04:56He lets her know just that on his wedding day.
04:59Eschewing the usual trappings of a sitcom, there's no punchline to spoil this moment.
05:04Instead, we get a heartwarming mother-son exchange that sums up the love they share.
05:09I mean for everything.
05:12My whole life.
05:17Knowing what we know now from young Sheldon, his gratitude carries so much more weight.
05:22She might not know it, but Mary's inspired him in more ways than one.
05:26Once again, her words of wisdom shine through, providing Sheldon with the epiphany that ultimately wins him and Amy a Nobel Prize.
05:34Sometimes it's the imperfect stuff that makes things perfect.
05:45Excuse me.
05:51Case in point.
05:53Number six. Sheldon gets baptized for Mary.
05:56People deal with grief in different ways.
05:58Turns out, Sheldon deals with his by becoming the best version of himself.
06:03The Cooper household is devastated by George's sudden passing.
06:06Despite his lack of faith, Sheldon agrees to be baptized to support his mother.
06:11But I'm watching my daughter fall apart right now.
06:17I'm just asking for 20 minutes of your time.
06:23Please.
06:27Fine.
06:28Okay.
06:29Between him and Missy, most fans would have expected Sheldon to back out.
06:33However, it's Sheldon who stays by his mother's side, refusing to abandon her when she needs him.
06:39Are you gonna go too?
06:40I know you don't believe.
06:44I don't, but I believe in you.
06:49Although the way he gets baptized is as hilariously Sheldon as it gets, it's the thought that counts.
06:55He doesn't share her religious faith, but nothing is stronger than Sheldon's faith in his mother.
07:00He proves this earlier on, standing up to the entire church for Mary's honor.
07:05And you went through with it just to please your mother.
07:08Well, she may not have understood me, or the things I cared about.
07:13But she did everything she could for me.
07:15Number 5. Mary worries for Sheldon.
07:18There are multiple references to Mary having Sheldon tested as a child in the Big Bang Theory.
07:23I had him tested as a child.
07:26Doctor says he's fine.
07:28Told you.
07:29Although I do regret not following up with that specialist in Houston.
07:33While that isn't exactly what happens in Young Sheldon, we do come close enough.
07:38Don't look at me. He's your kid.
07:40We know that it's just Sheldon being Sheldon, but a comedy of errors nearly convinces Mary otherwise.
07:46The duo ends up butting heads after Sheldon figures it out.
07:50Is it okay if I use a knife to butter my toast, or are you worried about me?
07:54I'm worried about you.
07:56I'm worried about you.
07:58I'm worried about you.
08:00I'm worried about you.
08:02I'm worried about you.
08:04I'm worried about you.
08:06Is it okay if I use a knife to butter my toast, or are you worried I'll do something crazy with it?
08:11You can butter your own toast.
08:13Oh good, you see the toast too. I was afraid I was imagining it.
08:16Eventually though, an honest conversation about Doctor Sturges' struggles and the topic of mental health clears things up.
08:23Yes, humor is one of their defining traits.
08:26However, the true strength of Sheldon and Mary's dynamic is built around love and compromise.
08:32Do you think since he and I are both gifted I'm going to end up like him?
08:38Well, it crossed my mind.
08:41No matter how much they clash, their bond is stronger than their differences.
08:46I'm sorry I caused you so much concern.
08:52I'm not.
08:57See how valuable a little communication can be?
08:59You do not take credit for this.
09:02Sheldon wants his mom to himself.
09:04To call Sheldon a mama's boy, or even a meemaw's boy, is putting it lightly.
09:09It doesn't matter if he's a grown adult.
09:11He wants Mary to dote on him.
09:13She just got off the plane. She doesn't want to cook.
09:15Well, of course she does. Making me food is her way of saying I love you.
09:19Making me food when she's too tired to cook is her way of saying I really love you.
09:24This becomes a problem when Mary visits Pasadena and spends time with Sheldon's social circle.
09:29Jealous of his friends for stealing her attention, let's just say Sheldon doesn't take it too well.
09:36I want to go sightseeing, so why don't you have some pancakes, get dressed, and come with us?
09:41I'm not going, and you can't make me.
09:44You're right, I can't. Have a nice day.
09:47It isn't until he falls ill that Sheldon gets what he wanted all along.
09:51The episode leans into Sheldon's over-the-top silliness, but also wraps it in a wholesome bow.
09:57While we all know Sheldon's in the wrong, there's something endearing about him wanting to remain the apple of his mother's eye.
10:04Mom is here to take care of her baby.
10:07Just to be clear, only her baby and not these other people?
10:11Of course.
10:13Can I have tea with honey and toast with the crust cut off?
10:16You can have whatever you want.
10:19Thanks, Mom. You're the best.
10:22Sheldon helps Mary regain her faith.
10:24Faced with a tragedy and many questions she can't answer, Mary finds herself at a crossroads.
10:30How could that possibly be true?
10:33How could a better place be anywhere but home, safe with her family?
10:38Having lived a certain way all her life, she struggles to function.
10:42Even Sheldon, who usually doesn't notice anyone's problems but his own,
10:46realizes his mother is distressed.
10:48Sheldon isn't the person you turn to when dealing with a crisis of faith,
10:52but he's the one who helps Mary overcome hers.
10:55Applying his logic-based outlook to a faith-based one, Sheldon reinvigorates Mary's lost spirit.
11:01Why are you trying to convince me to believe in God?
11:04You don't believe in God.
11:06I don't, but the precision of the universe at least makes it logical to conclude there's a creator.
11:12An unmendable emotional wound is healed through the words of her innocent, albeit genius, child.
11:17Sheldon may not believe, but for Mary, he's her special gift sent from God.
11:22There are five billion people on this planet and you're the perfect mom for me.
11:27What are the odds of that?
11:30It takes quite a while before Sheldon accepts that Amy is more than a girl who's his friend, but not his girlfriend.
11:37After a falling out with her, his denial manifests into an unhealthy obsession with cats.
11:42Oh, no.
11:45Robert, I'm sorry.
11:46I'm sorry.
11:47I'm sorry.
11:48I'm sorry.
11:49I'm sorry.
11:50I'm sorry.
11:51I'm sorry.
11:52I'm sorry.
11:53I'm sorry.
11:54I'm sorry.
11:55I'm sorry.
11:56I'm sorry.
11:57I'm sorry.
11:58Robert Oppenheimer was lonely.
12:01So you decided to get the whole Manhattan Project?
12:05Yes.
12:06Mary thinks she's seen every wacky thing Sheldon can do, but even she isn't prepared for this particular meltdown.
12:12However, it isn't long before Dr. Cooper's mom comes up with a sly solution.
12:17You two are definitely not suited for each other.
12:21That's a peculiar conclusion.
12:23By any standard, Amy is more similar to me than anyone I've ever met.
12:27Oh, I'm sorry, Shelly.
12:28I can't see it.
12:30With a bit of clever reverse psychology, Mary brings Shamey back together without either one catching on.
12:36Persevering her son's ego and getting him to drop the cat craze at the same time, Mary plays him like a fiddle, the way only she knows how.
12:45I saw what you did there.
12:46Amy thinks he's such a smarty-pants.
12:48He's no different from any man.
12:50You tell him not to do something, that's all they want to do.
12:53Before we unveil our top pick, here are a few honorable mentions.
12:57Sheldon accepts his mother's flaws.
12:59She's the best person he knows, but she's human, too.
13:03But I don't want to stand in the way of your happiness, so I'll condemn you internally while maintaining an outward appearance of acceptance.
13:14That is very Christian of you.
13:17Mary consoles Sheldon.
13:19When he had no friends, he had his mother.
13:22The announcements are starting.
13:25You want me to stay?
13:32I'll be in my room if you need me.
13:34Mary teaches Sheldon respect.
13:36That extra zing really does the trick.
13:39I will not have you be disrespectful to me.
13:41But you're not my mother.
13:42Don't you be disrespectful to her!
13:44Yes, ma'am.
13:46You'll get there, you just gotta put some zing on it.
13:50Faith vs. Evolution.
13:52There's no arguing with mommy, dearest.
13:54Everyone's entitled to their opinion.
13:56Evolution isn't an opinion, it's fact.
13:59And that is your opinion.
14:05I forgive you, let's go home.
14:07Mary forces Sheldon to apologize to Penny.
14:10Sheldon falls to his kryptonite.
14:13No, that's not fair!
14:16Why should I have to apologize?
14:19I really don't think this is the kind of thing Jesus concerns himself with.
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14:40Mary chases Sheldon.
14:43Any TBBT fan worth their salt knows Soft Kitty by heart.
14:47Sheldon's go-to song to feel better has been sung by Penny, Amy, and Mary, of course.
14:53I will always sing you Soft Kitty.
14:57Soft kitty, warm kitty, little ball of fur.
15:03Chronologically, we first hear the lullaby in young Sheldon.
15:06When Sheldon confines himself to the garage due to his germophobia, Mary comes calling.
15:12Although she tries to reason with him, she quickly reaches the end of her tether.
15:16You can't run away from me forever.
15:18I don't have to do it forever just till you get tired.
15:21Mary, I'm gonna run and go get my video camera. Don't catch him till I get back.
15:25With negotiations cut short, things spiral into an all-out chase sequence.
15:30But let's admit it, Meemaw's amused reaction is exactly how the rest of us feel watching the mother-son duo.
15:36I think I'm gonna wet myself.
15:38Get to the computer, Sheldon.
15:41Still, as it always goes, things end on a heartwarming note.
15:45Though Sheldon does fall ill, the warmth of Mary's soothing voice nurses him back to health.
15:51Soft kitty, warm kitty, little ball of fur.
15:57Happy kitty, sleepy kitty, purr, purr, purr.
16:03Did any other Sheldon-Mary moment make you go, aww?
16:07Let us know in the comments.
16:09Thank you, Lord, for this little boy.
16:13I knew I could fix it.
16:15Do you agree with our picks?
16:17Check out this other recent clip from Ms. Mojo.
16:19And be sure to subscribe and ring the bell to be notified about our latest videos.

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