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00:00 Hungarian scientist Katalin Karikó and US colleague Drew Weissman, who met in line for
00:06 a photocopier before making myrna molecule discoveries that paved the way for COVID-19
00:11 vaccines, won the 2023 Nobel Prize for Medicine on Monday.
00:16 The laureates contributed to the unprecedented rate of vaccine development during one of
00:21 the greatest threats to human health in modern times, the Swedish award-giving body said
00:25 in the latest accolade for the pair.
00:28 The prize, among the most prestigious in the scientific world, was selected by the Nobel
00:33 Assembly of Sweden's Karolinska Institute Medical University and comes with 11 million
00:38 Swedish crowns about 1 million dollars to share between them.
00:42 Karikó, a former senior vice president and head of RNA protein replacement at German
00:48 biotech firm BioNTech, is a professor at the University of Schiedschen, Hungary and adjunct
00:53 professor at the University of Pennsylvania Uppen.
00:57 We are not working for any kind of reward, Karikó who struggled for years to find grants
01:01 for her research, said in remarks alongside Weissman at Uppen's Philadelphia campus, a
01:07 few hours after she was awoken by the call from Stockholm.
01:10 The importance was to have a product which is helpful.
01:14 Co-winner Weissman, a professor in vaccine research also at Uppen, said it was a lifetime
01:19 dream to win, and recalled working intensely with Karikó for more than 20 years, including
01:25 middle-of-the-night emails as they both suffered disturbed sleep.
01:29 In 2005, Karikó and Weissman developed so-called nucleoside-based modifications, which stopped
01:35 the immune system from launching an inflammatory attack against lab-made myrna, previously
01:40 seen as a major hurdle against any therapeutic use of the technology.
01:45 We couldn't get people to notice RNA as something interesting, Weissman said on Monday.
01:50 Pretty much everybody gave up on it.
01:52 (upbeat music)