S2E1: 1%-5% of Patients with Chronic Pain Develop THIS!
This couldn't be... perhaps... intentional...
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00:00:00Amy, it's good to be back, and we're starting what we're going to call our second session.
00:00:11As you know, we did these podcasts for about six months, and we did them weekly.
00:00:19At the time they ended, I kind of thought we would be finished, but it turns out that
00:00:25sort of by popular demand, we are back.
00:00:29And we're back for really one basic reason, and that is we still have an awful lot of
00:00:37people in the United States and in the Western world who are not getting adequate pain treatment,
00:00:44and they just don't know what to do.
00:00:47They're lost, and the purpose of this is very simple, and that is to try and bring better
00:00:53treatment to those people who have intractable pain.
00:00:58It's as simple as that.
00:00:59Now, I'd like to get us started a little bit by going over a couple of things that are
00:01:05on my mind and that I want our audience to know about.
00:01:11And first off, this podcast is not for the average pain patient.
00:01:16It is for that unusual group of people who have what we would call intractable pain.
00:01:24They're those who have a disease that gives them a significant pain that makes them miserable,
00:01:30shortens their life, and ruins whatever life they might have.
00:01:34Now, let me, first off, I want to give out a few statistics.
00:01:38Now, the statistics in dealing with pain are hard to come by, and they're very broad and
00:01:44general.
00:01:45But I think it needs to be said because there's something about the whole ambiance, if you
00:01:53will, or the whole pain population in the country that's not well appreciated.
00:01:58Now, first off, you see all kinds of publications which are really misleading.
00:02:04They're misleading because they talk about millions of pain patients in this country.
00:02:08That's true.
00:02:09However, 80% of those people are in very good treatment.
00:02:15They're not impaired.
00:02:16They're getting good treatment.
00:02:18They have a mild form of pain, and they can be taken care of by their local chiropractor,
00:02:23physical therapist, or even self-help.
00:02:26In fact, I've got a couple of publications, in fact, you may get them also, where somebody's
00:02:31sending out a new catalog that if you just buy this supplement, your neuropathy or arthropathy
00:02:37will go away and will be controlled.
00:02:40And guess what?
00:02:41That's probably true in 80% of the cases.
00:02:45So when you start talking about pain in this country, you're talking about the vast, vast
00:02:52majority do not have intractable pain, they're in good treatment hands, there's plenty of
00:02:57options out there.
00:02:59That's not what this podcast is about.
00:03:02This podcast is about a very small group of people, really.
00:03:06Now you've got 80% of those people who are doing very well.
00:03:09They don't need me.
00:03:10They don't need this podcast.
00:03:11They don't need the government.
00:03:12They don't need much of anything.
00:03:13They're doing just fine.
00:03:14Now you've got another 15% or percentage, or I'm going to guess somewhere between another
00:03:2213% and 17% in any way, who have a degree of pain that is nagging to them.
00:03:34It bothers them some days, they can't maybe work on some days, they've got migraines,
00:03:38they've got rheumatoid arthritis, they've got diabetic neuropathy, they've got some
00:03:42condition that needs some medical treatment and may lay you up for a day or two, but it's
00:03:51not intractable.
00:03:53It's not a real problem.
00:03:54Those people are getting help also.
00:03:56I mean, every doctor, every nurse practitioner, every PA, every physical therapist, every
00:04:03massage therapist, every fitness center, every personal coach has got some of those 15% and
00:04:11they're doing pretty well.
00:04:13That's not what this show is about.
00:04:16What I'm here to talk about are those 5% and may not even be 5%, maybe 1%, but somewhere
00:04:24between 1% and 5% of people who have pain have what we would call intractable pain or
00:04:31even what we call intractable pain syndrome.
00:04:34Those are the people who are suffering the most.
00:04:37I see some of you are regulars with this show and that's who we're targeting.
00:04:42We're targeting at that 5% of people who really need all the help they can get.
00:04:49And now let's talk about the 5% for just a minute.
00:04:52We hear from them every day.
00:04:54We hear from them, they can't get help in a lot of cases.
00:04:58They want to commit suicide in a lot of cases.
00:05:01They're getting some help, but they're still miserable.
00:05:03Some are confined to bed, some are ready to give it up.
00:05:07That's who we're talking about right now.
00:05:09But I want to make another point.
00:05:12Among this 1% to 5%, there's still a very small group and this is why the government
00:05:20and a lot of people who are trying to advocate for more opioids or for better treatment aren't
00:05:25getting very far because the politicians, for example, in Washington are far more concerned
00:05:31about people on the street overdosing than they are people with intractable pain.
00:05:36Why?
00:05:37There are more of them.
00:05:38You've got to remember, people with severe intractable pain is a very small number.
00:05:43We don't have any political clout.
00:05:45However, I will say this, let me give you some good news.
00:05:51It's spotty throughout the country.
00:05:53So when you make a statement about pain, you've got to remember you're talking about Maine,
00:05:56you're talking about Georgia, and you're talking about Oregon, and none of these states are
00:06:00the same because pain treatment is a state issue, legally and by our constitution, where
00:06:08a republic and each state sets its own medical guidelines.
00:06:13So when we make a generalized statement, we've got to be a little careful because what they're
00:06:16doing in Maine, which is doing pretty well incidentally, isn't the same as they're doing
00:06:20in Colorado.
00:06:22But as we talk here, let me give you some good news.
00:06:26First off, we do have some states, Colorado I think is the most recent one, who do have
00:06:32a lot of concerned legislators and they are, again, showing some pity, and that's what
00:06:37it is.
00:06:38In order to get any laws passed, it's got to be a sense of pity and mercy on the part
00:06:44of your legislature and your governor because we're a small number.
00:06:49We're not going to get anybody elected.
00:06:51We're not going to give anybody any great contributions or credit.
00:06:54We're not enough of it.
00:06:56So we're a small group, but in the states, they are hearing a lot of people's cries.
00:07:02They are starting to do some things, and that really is good news.
00:07:06But I want to make you aware that, no, we're never going to have enough people to march
00:07:11on Washington or be politically influential, except to say, look, we got a problem.
00:07:16We would like a little help, and I think we're starting to get it.
00:07:19So I think that's a good sign.
00:07:22The other good sign that I see out there, and again, it's spotty because I do know some
00:07:27people watching this program can't get any help, but doctors throughout the country are
00:07:32also seeing the need to treat this one to five percent, okay?
00:07:40And some are getting very good at it.
00:07:42Some are starting to recognize that what was the pain specialty really isn't a pain specialty.
00:07:49It's a profession to use certain tools to help pain, but it's not a pain specialty that's
00:07:55going to diagnose your problem, going to treat you medically or psychologically.
00:07:59They're going to do a procedure or two to try to see if they can't help you.
00:08:05But nationwide, we are starting to see doctors, nurse practitioners, PAs everywhere starting
00:08:14to take on patients, and we're far better off today than we were, let's say, five years
00:08:21ago, three years ago.
00:08:23For example, and now I want to get to something else.
00:08:26For example, let's take adhesive arachnoiditis.
00:08:29Three or four years ago, they'd hardly heard of it.
00:08:31Well, now they've normally heard of it, they're starting to diagnose it, and they're starting
00:08:35to treat it.
00:08:36Now, which gets me on to the next thing I do want to talk about.
00:08:40Who are these people who are in the 1% to 5%?
00:08:45These are a little different group of people than they were, let's say, 20 years ago.
00:08:53If you were to have visited my clinic 20 years ago, 30 years ago, 40 years ago, you would
00:08:59have seen people there who had rheumatoid arthritis, systemic lupus, you would have
00:09:05seen people with diabetic neuropathies, you would have seen people with interstitial cystitis,
00:09:09a lot of pancreatitis.
00:09:10Now, what am I getting at?
00:09:13A lot of those diseases now have specific treatments.
00:09:18For example, we didn't used to have a sickle cell treatment, now we've got a couple of
00:09:22things that work pretty good, same way with interstitial cystitis.
00:09:27And so a lot of the conditions that caused intractable pain some 10, 20, 30 years ago
00:09:36have specific treatments.
00:09:38So those people have kind of dropped out of what we call the pool.
00:09:42They're now in the 15% getting some help, not the 5% who are desperate and really have
00:09:49a terrible problem.
00:09:51So what's left?
00:09:53Today, and I've gone into several clinics lately, and I'm looking at a lot of data all
00:09:58the time, there's really only a couple of conditions that are throwing people into the
00:10:055%.
00:10:08And one of the reasons why we're going to keep this podcast going for a while is to
00:10:11get totally the patients and the families, but practitioners everywhere, understanding
00:10:18who this 5% is.
00:10:20Now there are two conditions that make up most of the 5%.
00:10:25One is adhesive arachnoid items, that's probably number one today.
00:10:30Number two is probably reflex sympathetic dystrophy or CRPS.
00:10:35Some people are calling just severe neuropathy CRPS, they have CRPS, it's supposed to be
00:10:39initiated by trauma, but people who have got severe neuropathies are calling it that, and
00:10:46that's okay.
00:10:47It's still a severe neuropathy.
00:10:49The third most common condition is probably head trauma, including strokes.
00:10:56And so you've got what I call the big three.
00:10:58You've got adhesive arachnoiditis, you've got severe neuropathies, which most people
00:11:03like to call CRPS today.
00:11:05And thirdly, you've got head trauma, including those people who, trauma is caused by strokes
00:11:12or meningitis or some other brain disease.
00:11:16Now we still have a handful of people who have such severe pancreatitis or lupus or
00:11:22something that just hasn't responded, but fundamentally we've got these three conditions.
00:11:30Now the other thing that's come out of our research, which gives us some hope, is that
00:11:36these three conditions tend to be very aggravated or maybe even caused by the genetic connective
00:11:45tissue diseases.
00:11:47These are being recognized now throughout the country, although there isn't a week goes
00:11:52by that somebody asks me, well, what is Ehlers-Danlos syndrome?
00:11:57I see all kinds of reports from insurance companies, medical boards, hospitals, and
00:12:02they say, well, how do you diagnose it?
00:12:04Well, very few people even know what a Brighton score is.
00:12:08And I just recently reviewed a couple of cases of which doctors are in trouble with their
00:12:12medical boards because they said the person had EDS, or Ehlers-Danlos, but didn't know
00:12:18how to diagnose it.
00:12:19They just said they had it and it wasn't good enough.
00:12:21They had to diagnose it by a Brighton score.
00:12:24So we're going to talk about the Brighton score on this program a little bit.
00:12:28If you've got EDS, or genetic connective tissue disease, you better have a Brighton score,
00:12:34and you better know how that's done, you better know who Dr. Brighton was.
00:12:38Now the other thing that is really kind of shocking, and you've heard me talk about this
00:12:45before, at least those who have followed my work, is that we now know that we have some
00:12:50parasites in the human body that can activate and give what's called an autoimmune diathesis,
00:12:58or an autoimmune situation.
00:13:03The most common one is the Epstein-Barr virus.
00:13:07That's the one that causes infectious mononucleosis.
00:13:10But we know that virus is a parasite.
00:13:12It's in all of us humans.
00:13:15And we now know that under certain circumstances, it can activate, grow, bud, if you will, and
00:13:22put out toxins, or invade nerves, and aggravate conditions like adhesive arachnoiditis, or
00:13:30maybe even lead up to it.
00:13:32And so another common parasite that we're now starting to identify, for example, there's
00:13:38one called cytomegalic disease, Lyme is probably in this category, certain of the herpes viruses.
00:13:45Lung COVID may be just another name for a parasite or a virus that's fighting in all
00:13:51of us.
00:13:52There are lymphocytes or nerves that is causing an autoimmune problem.
00:13:57And now, again, this term autoimmune, I love to talk about it because no one quite knows
00:14:06what it means.
00:14:07Some of you who watch this program do.
00:14:09Autoimmune is a misnomer.
00:14:11Autoimmunity means that you're resistant to somebody, something.
00:14:15You'd think that autoimmune means that you're automatically resistant to somebody, and that's
00:14:19not true.
00:14:20What autoimmune means, and I'm dead sorry that we even have this term, it means that
00:14:28your body has some element that is destroying your own tissue.
00:14:35Now we used to think that was always an antibody of some kind, but we now know it can be a
00:14:38toxin of some kind, or it can be an invasion.
00:14:44But nevertheless, autoimmune means you've got some element that is eating away at some
00:14:49of your tissues.
00:14:51Today, I don't believe I've seen a single person who's got severe CRPS or disease of
00:15:01arachnoiditis or severe head trauma who doesn't have some parasite that seems to be acting
00:15:09up and adding to the autoimmunity and accelerating the problem.
00:15:13The good news is that we're learning how to suppress those parasites pretty fast, okay?
00:15:17And I'm going to talk about that in a few minutes.
00:15:21Because what I was afraid of here a year or so ago was that we wouldn't be able to suppress
00:15:25the Epstein-Barr virus or cytomegalic disease or some of them, but turns out that's not
00:15:31true.
00:15:32We've got pretty good ideas on how to suppress these viruses now, and that's part of the
00:15:36protocols these days.
00:15:40I want to move on now to another thing that I feel very strongly about.
00:15:47When it comes to intractable pain, regardless of your cause, you need to treat it with what
00:15:55I call a three-component medical protocol.
00:15:59I hope that doesn't sound too long or too complex.
00:16:02It's not.
00:16:03As a matter of fact, most doctors know about this instinctively, but they don't do it,
00:16:08you might say, in a good programmatic style, I guess the job done.
00:16:13So if we're talking about a three-component medical protocol, it's very, very simple.
00:16:17Component number one, you've got to suppress the inflammation and the autoimmunity.
00:16:23Number two, you've got to try to heal some tissues or regenerate damaged tissue.
00:16:30And thirdly, you're going to have to have some pain control.
00:16:35You got to do all three.
00:16:37Now this is hardly new.
00:16:39I always like to tell the story of the Brompton cocktail, which was invented in 1895.
00:16:46And in 1895, the doctors then knew that you might need to take an opioid, you needed to
00:16:54take what's called a GABA agonist, which I may talk about in a little bit.
00:16:58That was alcohol in those days, or you needed to have what's called a dopamine surrogate.
00:17:02In those days, that was cocaine, today that's things like Ritalin or Adderall.
00:17:09And they also needed an anti-inflammatory agent.
00:17:13So you had to have those four things, and that was part of the Brompton cocktail.
00:17:16And anyway, somehow or another, this has gotten lost in the shuffle, and I hardly ever
00:17:21see a medical report that's getting all four components.
00:17:28All three of the components, plus something for inflammation.
00:17:32So why are we here?
00:17:33I guess you could all boil it down to preaching about the four things you got to have to treat
00:17:38severe intractable pain.
00:17:40And if you leave any one of the four out, good luck, you're not going to get much relief.
00:17:45And so we're sure to get the word out there.
00:17:48Okay, now, and then let me talk about the next reason on why we're doing this podcast.
00:17:54We're short of doctors.
00:17:57We're short of nurse practitioners.
00:17:59Maybe not by count, but we are short by those who are willing and able to treat intractable
00:18:07pain patients, okay?
00:18:11Every day, I hear from somebody who says, well, what specialist do I call to get help?
00:18:16I don't know.
00:18:17There is no specialist.
00:18:20The hard message out there is there is no one who specializes in adhesive arachnoid
00:18:25itis, CRPS, head trauma, or intractable pain.
00:18:30And that's why you're going to, right now, there is the burden of everybody who has one
00:18:36of these conditions to try to find some local help.
00:18:41And that's very hard.
00:18:43And even if you find some help and you find a good-hearted physician, you find a competent
00:18:48nurse practitioner, they may not know anything about your problem.
00:18:53And so we've got the burden of trying to educate them.
00:18:57Now, we have the other burden we have, and I'm looking here right on this show, we've
00:19:03got somebody here from one state and then we've got another state.
00:19:06If we had all the intractable pain patients in one state, or one city, or one neighborhood,
00:19:11we could call a self-help meeting and bring in a few doctors and get the job done.
00:19:16The problem is that we've got one or two patients in this city and a couple more in that city
00:19:20and three or four more in this state or that state, and so we're all spread out.
00:19:25That is the problem with a rare condition.
00:19:30And so we've got, if not a rare condition, it's an unusual condition.
00:19:33So all the patients are spread out, and that's why I encourage everybody at least to be on
00:19:39some Facebook groups or social media groups to where you can talk about your problem and
00:19:44share information.
00:19:45And just one quick caution, some of these social media groups can be awfully negative
00:19:50and only focus on pain treatment as opposed to disease treatment, which I'm going to get
00:19:56to in just a second.
00:19:57So again, and there's something else about medical care in this country at this time.
00:20:04Universities and states did not keep up with the population growth, and therefore doctors
00:20:11are very short in some locales in the country.
00:20:15Now to make up for this, we have one movement out there, and that's the osteopathic schools.
00:20:21They're springing up throughout the country, and if you see somebody that says they're
00:20:25a doctor and got a Neo behind their name, that means a doctor of osteopathy.
00:20:30They're putting out a lot of these people, and they're quite good, they're trained like
00:20:33MDs, and the problem they have is they don't go through the long-term training like people
00:20:39in my generation.
00:20:40We're putting out doctors today with no more than about eight years of schooling.
00:20:46Back in my day, it was a minimum of 12 in military, public health service, things like
00:20:50that.
00:20:51So you're going to have to face one thing.
00:20:53You are not going to get the well-trained physician out there like we used to have.
00:20:59Consequently, we're going to have to rely more on diagnosis.
00:21:04Now, let me move to my next subject that is very, very critical today, and that is, believe
00:21:15it or not, and this may sound kind of unbelievable, but it is a fact, and that is, pain management
00:21:24and pain treatment that grew up with the fifth vital sign did not encourage physicians or
00:21:30the medical system to diagnose the cause of pain.
00:21:33They just said, we're going to treat pain, and therefore, the fifth vital sign was pain
00:21:39in the 1 to 10 scale, but nobody ever said you ought to figure out the cause of the pain.
00:21:46Nobody ever said if you really want pain relief, you've got to treat the underlying cause.
00:21:51All the symptomatic pain treatment which we have, whether they're high-dose opioids, stimulators,
00:21:57intraplanet pumps, electromagnetic devices, or physical therapy, all those are symptomatic,
00:22:04and they are not eternal.
00:22:07And so, people think that they're going to solve this problem, they can just get enough
00:22:11opioids.
00:22:12I've got news for you.
00:22:13If you're not also treating the cause, which gave you a disease, which made you need that
00:22:21high-dose opioid, you're going to pay a penalty down the line.
00:22:25One of the tragedies we're starting to see right now, I hear from these people daily,
00:22:30we've had people who have taken high-dose opioids, and particularly if the opioids have
00:22:34been in a pump, and they've worn out their receptor sites, and the opioid no longer gives
00:22:38them pain relief.
00:22:39And one has to understand that if you don't know how to use opioids correctly, and you
00:22:47don't treat the underlying disease, it's never dawned on you that your opioids might stop
00:22:51working, and there is no dosage that will help.
00:22:56This does happen.
00:22:57It's not just tolerance.
00:22:59We now scientifically know that receptors are like rubber bands.
00:23:02If you stress them too far, you do too much to them too long, they don't work anymore.
00:23:08So we've got a lot of people in bed these days waiting just to die, because their receptors
00:23:14don't work anymore.
00:23:15And so this is a new part of pharmacology and pain treatment that people got to know
00:23:22about.
00:23:23Bottom line is, the best advances we have made in the last 30 years in pain treatment
00:23:30has been treating the underlying disease, not symptomatically trying to treat the pain.
00:23:37Okay?
00:23:38Now, let's go on with this for just a moment.
00:23:44One of my messages, maybe it's my most potent message, is that everybody who has intractable
00:23:51pain needs to know very specifically what caused that pain.
00:23:57What diseases do you have that is giving you intractable pain?
00:24:04What diseases do you have that's causing you to have autoimmunity?
00:24:08What disease do you have that's causing your intervertebral disc to degenerate?
00:24:13What disease do you have that is gluing your caudal equina to the arachnoid membrane?
00:24:19What disease do you have that is eroding away your small fibers and giving you small
00:24:24fiber neuropathy, or worse, giving you neuropathy of your motor nerves like your sciatic nerve?
00:24:31In other words, what is the disease or diseases that are causing these problems?
00:24:39But now let me give you the $64 question.
00:24:43Do you have tests and paperwork in your personal medical records at home that document this?
00:24:52Let me say it again.
00:24:56My big pitch today is this.
00:24:59Every person with intractable pain, and that means you've got pain every day and you're
00:25:04going to have to take medicines every day for it, do you have in your personal medical
00:25:08records at home, not in the doctor's office, not on your computer, not on your phone,
00:25:16in writing, in paper, the specific diseases you have that has caused your pain?
00:25:25For example, I've had some good news.
00:25:28I have been, of course, reading MRIs of people with each spine problem for quite some time.
00:25:34I thought most of it was all got to be an arachnoid diet as well.
00:25:38But it turns out there's a lot of other spinal conditions like tarlofus, like epidural fibrosis,
00:25:43like non-invasive arachnoiditis, or chronic cauda equina syndrome that gives you terrible pain.
00:25:51And we now see this.
00:25:53It's no longer acceptable to say you've got fatal back surgery syndrome.
00:25:57It's no longer acceptable to say you've got a degenerating disc disease.
00:26:01It's no longer acceptable to say I've got neuropathy.
00:26:04What kind of neuropathy?
00:26:06What caused those discs to degenerate?
00:26:09And so the good news is this.
00:26:12We've been taking MRIs and writing on them where the adhesive arachnoiditis, where the
00:26:18cauda equina is inflamed, where the discs are protruding, and sending this back to the
00:26:25patients.
00:26:26And they're taking that to their family doctor.
00:26:27And guess what?
00:26:28They're starting to get a good reception.
00:26:29They're starting to get some help.
00:26:32Yay.
00:26:33Okay?
00:26:35And we're also starting to hear that if they don't have that, they get sent out the door.
00:26:40Okay?
00:26:41So the bottom line is this.
00:26:44This is the day of diagnosis.
00:26:47If you don't have a diagnosis in your records, then you need to get on your horse and start
00:26:53getting them.
00:26:55You can't depend on them down at your local doctor or the image center or the laboratory
00:27:01or on your computer.
00:27:02That's not going to cut it.
00:27:03You've got to have something in your hand that you can take every visit to your medical
00:27:09practitioner.
00:27:10Now, let me talk about what diagnoses we've come up with in recent years.
00:27:14I'm shocked on how few people know about these things.
00:27:17I'm going to talk about three or four of them.
00:27:20Okay?
00:27:21Now, the first thing I'm going to talk about is the MRI.
00:27:24The new contrast MRIs are fantastic.
00:27:27I mean, you can look right in this.
00:27:30MRIs of the spine have two views, one from the side and then one from your toe to head.
00:27:37It's like looking straight up the body.
00:27:40It's like you're looking right into the soul, quite frankly.
00:27:42It's really amazing.
00:27:44With this new contrast technology, you can literally see where the discs are slipping
00:27:50out.
00:27:51You can literally see whether your arachnoid membrane is swollen.
00:27:56You can literally see if you've got scarring.
00:27:58You can literally see if the nerve roots have come together.
00:28:03You can literally see if you've got a tarlof sitting there in your spinal canal.
00:28:08And then you can back that up, take some blood tests, take some other tests and figure out
00:28:12what caused this.
00:28:14So everybody needs to have their own MRI copies.
00:28:20And incidentally, I see nothing wrong with picking up our little handbooks on how to
00:28:24look at MRIs.
00:28:25I see nothing wrong with lay people learning on how to tell the protruding or slipped discs
00:28:31from a regular one.
00:28:32I think in this day and age of technology, you should learn how to do this.
00:28:37My heavens, people are all the time learning how to do one thing or another.
00:28:42And now we're starting to talk about A1 technology.
00:28:45Well, at least you can look at a simple MRI of the lumbar spine.
00:28:49So I hope something has shown up here on my screen.
00:28:54I hope that means we're still recording.
00:28:56Yes.
00:28:57OK.
00:28:58Anyway, one of the things that I want everybody to know, when you go down to the laboratory,
00:29:06when you go down to the image center and you have those tests, they belong to you.
00:29:13OK, they're yours.
00:29:16And if somebody tells you they're not, I guess you could call a lawyer, but I would raise
00:29:21a fuss.
00:29:22They're yours and you've got to have them.
00:29:25If you, I mean, when you've got a rare disease, and keep in mind, if you're in that 5%, you
00:29:32need opioids every day, you've got to, you're miserable, you don't want to live.
00:29:36You got to remember, you've got to get that diagnosis, get all that, and it's certainly
00:29:41your right to yell, holler, and scream until you get that MRI and know what you're looking
00:29:47at.
00:29:48OK?
00:29:49I mean, think about it for just a minute.
00:29:51Nearly every woman in this country can get her mammogram, and if you can't get your mammogram,
00:29:58you can sure get the MRI of your lumbar spine, and so I'm recommending that everybody do
00:30:03that.
00:30:04Now, I'll have to admit, let me talk about some other diagnosis tools that have been
00:30:10developed.
00:30:11Let me talk about my other favorite ones for just a minute.
00:30:15Basically, I'm a laboratory guy.
00:30:19I'm an internist by background.
00:30:21We love laboratory tests.
00:30:22I love blood tests.
00:30:23I love urine tests.
00:30:24OK?
00:30:25Now, what blood tests are we talking about?
00:30:29If you need to take opioids every day of your life, you need to take a benzodiazepine every
00:30:35day of your life.
00:30:38If you've got pain that's putting you in bed every day of your life, frankly, you need
00:30:43some blood tests.
00:30:45Now, you need about three kinds.
00:30:48Number one, you need inflammatory markers.
00:30:51OK?
00:30:52How much inflammation do you have?
00:30:54Now, in the past, our inflammatory markers have been pretty crude.
00:30:59They go under the names of the erythrocyte sedimentation rate, the ESR, or the CRP.
00:31:04That stands for C-reactive protein.
00:31:06That's about all we've had.
00:31:08However, in recent years, we've developed what is called a cytokine panel.
00:31:14Now, a cytokine measures such things as, oh, they go by anti-inflammatory or pro-inflammatory
00:31:21markers.
00:31:22You don't need to know that, because they go under such names as leukotrienes and necrosis
00:31:28factors and that sort of thing.
00:31:29But you have a whole panel today that's been pioneered out of the University of Utah and
00:31:35laboratories in Utah, but nevertheless, they'll give you a whole readout of these cytokines.
00:31:43And if you've got an elevated one, that means that you've got too darn much inflammation
00:31:47somewhere in your body, and you better get that down to normal.
00:31:51OK?
00:31:52And everybody who's got daily pain ought to have a cytokine panel.
00:31:55Now, your doctor's probably going to look at you across the side and say, my God, I'm
00:32:00all for you, but I don't know how to read it.
00:32:02Well, we can get somebody to read it for you.
00:32:03It's no heart trouble at all.
00:32:06And so you need that.
00:32:08The second thing that you want that's out there is, they seem to come up with a new
00:32:16one almost every week, but there's a lot of what we call autoimmune markers.
00:32:20OK?
00:32:21All we used to have was one for rheumatoid arthritis or systemic lupus, but there's one
00:32:27out there that is standard, and it ought to be on everybody's medical chart, and that's
00:32:31what's called an ANA, Anti-Nuclear Autoantibiotic, an ANA.
00:32:39Everybody ought to have that on, and know whether they've got an elevated one.
00:32:42If you've got an elevated ANA, that means you've got a lot of autoimmunity.
00:32:45That's a pretty crude test, but nevertheless, we do have that one.
00:32:50Next thing you need is hormones.
00:32:53Now, I'd like to have a nickel for every five minutes that I've lectured on the doctors
00:33:02on getting hormone panels.
00:33:03I'd be a rich man if I got my nickel, but anyway, it used to be that hormones were almost
00:33:10couldn't be ordered or accessed by doctors.
00:33:16They were very expensive, the technology wasn't there.
00:33:22Today, they can do a hormone panel just like they do a cytokine panel, and it's pretty
00:33:28inexpensive.
00:33:29In other words, with one blood tube, you can get your testosterone, your estrogen, your
00:33:34progesterone, your DHEA, and your pregnenolone.
00:33:40You can get all those tests at one time on one tube of blood, and also, you get your
00:33:45cortisol level in there also.
00:33:48Hormones are really essential, and why?
00:33:50I'll tell you something else that I've just recently learned.
00:33:54Anybody had a pain flare lately?
00:33:55Sure you have.
00:33:57One of the big things that we found out is, it causes pain flares all the time is low
00:34:02pregnenolone levels.
00:34:03Now, most people have never heard of pregnenolone, much less be able to spell it, but pregnenolone
00:34:08is one that makes everything else.
00:34:09This might shock you, there's one hormone that makes all your hormones in your adrenal
00:34:16gland and your ovary and your testicles, called pregnenolone, and it's also been shown that
00:34:22that heals everything in the spinal canal.
00:34:26Anybody who's got daily pain, frankly, I know this is coming out of the blue, but everybody
00:34:31ought to know what their pregnenolone level is, and have it measured every six months,
00:34:35and if it's low, you're going to need to take it.
00:34:39DHEA.
00:34:40DHEA is what they call a pro-hormone, that D and that H and that E and the A all stand
00:34:45for different things, but bottom line is, it makes your testosterone, your estrogen,
00:34:49and it makes something called nandrolone, which we now are giving for people with things
00:34:54like RSD and AA, meaning adhesive arachnoiditis.
00:35:00Now, the last laboratory test that are really critical out there is your Epstein-Barr viral
00:35:07antibodies, and you might as well throw in some of the herpes antibodies and some of
00:35:12your cytomegalic antibodies, but we know that everybody really needs to know if that Epstein-Barr
00:35:19virus has activated in them.
00:35:23It doesn't cause your problem, but it'll make your problem worse, because it causes
00:35:28a lot of autoimmunity, and I'm going to say a couple more words about how to control Epstein-Barr
00:35:33virus, because I do have some good news on that.
00:35:35So, anyway, laboratory tests are critical, and now let me talk about a couple of laboratory
00:35:41tests that might surprise you.
00:35:43The next is, they've come up, you've all heard of an electrogram, a cardiogram, an electroencephalogram,
00:35:49now they've got electrobiograms, and they've even got more sophisticated electrodiagnostic
00:35:56equipment.
00:35:57Some of it is not very accessible, but I do, I can tell you that I have seen electromagnetic
00:36:04diagnostic testing in which you can pin down exactly which nerve coming out of the spinal
00:36:10cord is the problem, and where your pain is being generated.
00:36:14I've seen that technology, I hope it's not available yet very much, but it's out there
00:36:19and I hope it spreads.
00:36:21The last one I want to talk about is one that I want all of you folks out there who have
00:36:26had fibrobiology, EDS, hypothyroidism, or some diagnosis that nobody says they understand
00:36:39or they don't believe you, and we have now learned something terribly important.
00:36:46When you develop an autoimmune problem, because you've got EDS, or Epstein-Barr, or any other
00:36:55genetic disease, you're going to develop something called small fiber neuropathy.
00:37:02What does that mean?
00:37:03That's what causes your pain all over.
00:37:07Everybody out there has woke up and you've got pain from head to toe, right?
00:37:11What's causing that is that the small fibers have been burned out and can no longer conduct
00:37:19your pain, so therefore you may wake up one day and have pain on your lower leg, the next
00:37:24day on your back, on your arm.
00:37:26Why?
00:37:27Because those small fibers are burned out due to your autoimmunity and your basic disease.
00:37:34What does that mean?
00:37:35We now have biopsies for that.
00:37:38If you doctors don't know what you've got, you better guess what's called a small fiber
00:37:42biopsy.
00:37:44That's hardcore evidence that you've got severe intractable pain.
00:37:51Those biopsies are being done throughout the country right now.
00:37:54Doctors are learning to do them all over, they're easy to get, they were a little rare
00:37:57and hard to get, but I did want to tell you that if they're asking you what you have and
00:38:02you don't have a diagnosis, you need a small fiber biopsy.
00:38:05Okay?
00:38:06All right, let me just review the laboratory test.
00:38:08I know this is new, but I'm going to cover them again, MRIs, new blood tests, some electromagnetic
00:38:17testing and small fiber biopsies.
00:38:20These are all new diagnostic tools and let me go even a step further.
00:38:26I'm now telling everybody to diagnose that case, have that in your medical records.
00:38:35Can't begin to tell you on how that throughout the last 20 years, the standard has been to
00:38:43go ahead and treat pain without a diagnosis of the underlying disease.
00:38:48And now I think that's caused an awful lot of problems with medical boards and maybe
00:38:52even the federal government.
00:38:54You've got to have a diagnosis.
00:38:55Okay?
00:38:56And some of you I know don't have it, can't get it, but you're going to have to start
00:39:02trying to get it.
00:39:03Okay?
00:39:04It may take you a little while, you may have to educate your doctors, you may have to be
00:39:07a little pushy, but you've got to know what you have.
00:39:10And quite frankly, if I was a doctor today and you come in to me and tell me you've got
00:39:16a bad back, you've got EDS, you've got fibromyalgia, I'd send you packing.
00:39:25Unless, unless you've got the diagnostic tools and records in your hand showing that you
00:39:35have got a legitimate and tractable pain disease.
00:39:38Okay?
00:39:39Now what's caused this?
00:39:41Fraud.
00:39:42The underground has learned how to walk in the doctor's offices and say they've got EDS,
00:39:49they've got fibromyalgia, they've got neuropathy, they've got failed back, they've got even
00:39:54arachnoiditis, and they say this to get opioid, to get benzodiazepines.
00:39:59Okay?
00:40:00So you're going to have to show that you're not one of those.
00:40:07So you can't put a doctor or a nurse practitioner in most towns in this country on the spot
00:40:15by telling them, I've got intractable pain and all my doctors said so and I've been taking
00:40:21opioids for years.
00:40:22That's not going to cut it.
00:40:23It's my recommendation, make sure you're aware of this.
00:40:29Before you are able to get daily opioids in this country, you need that diagnosis.
00:40:35Now the reason I'm saying this, the diagnostic tools are available now.
00:40:40They weren't available 10 years ago, five years ago even.
00:40:44But they are today and that's a major, major change in my way of thinking on the ability
00:40:51to get opioid drugs.
00:40:53You want to take 500 milligrams of morphine equivalents a day?
00:40:57Where's your blood test?
00:40:58Where's your MRIs?
00:40:59Where's your small fiber biopsy?
00:41:02You see what I'm coming at?
00:41:03You're going to have to be able to prove with objective evidence that you have it.
00:41:09A doctor's referral is not going to be good.
00:41:12Our original Intractable Pain Act, incidentally, don't even mention diagnosis.
00:41:17I wrote them clear back in the 1990s and all we said was if you had two doctors that agreed
00:41:24you've got intractable pain, you can get opioids.
00:41:28Not today.
00:41:29You're going to have to have diagnostic documentation, in my opinion, and that is to protect the
00:41:36enforcement agencies and the doctor and the patient.
00:41:39Let's call it a deal.
00:41:41Let's show that we really have a condition that needs these opioids.
00:41:46I think that's our only way to resolve the situation where we can't get people home.
00:41:54No diagnosis, no treatment.
00:41:56Okay?
00:41:57I'm going to repeat that.
00:41:58I know that's a hard message to some people.
00:42:01No diagnosis, no treatment.
00:42:03Okay?
00:42:04It's got to be that way today.
00:42:05All right.
00:42:06I want to move on to a couple of other subjects.
00:42:12When it comes to treatment today, I'm just very, very personally frustrated.
00:42:20We have known since 1895 when they had the Brompton cocktail how to treat pain.
00:42:26We've known since the Civil War how to create laudanum.
00:42:30You know what laudanum was?
00:42:33Laudanum was like the Brompton cocktail.
00:42:34It had opium in it, it had alcohol in it, it had some other compounds in it.
00:42:40That was a better treatment drug than people are getting today.
00:42:43Interesting.
00:42:44We had better pain treatment in the 1800s than we do now.
00:42:50Okay?
00:42:51A plain opioid is okay, but it's not going to get you where you need to be.
00:42:57Now, why this doesn't sell, I don't know.
00:43:03We have something in this country called palliative care, theoretically.
00:43:07Now, what is palliative care?
00:43:10The definition of palliative care is care that is symptomatic to provide mercy and to
00:43:17give people a quality of life and some decent way to live out their life.
00:43:23Okay?
00:43:24Whether that's six months or six years.
00:43:27It isn't supposed to be just cancer.
00:43:31It's supposed to be any condition that is incurable.
00:43:35And if you have a terrible pain that has an incurable disease, you're supposed to be able
00:43:39to get palliative care, supposedly, at whatever dosage or whatever drug you need.
00:43:46Everybody is out there harping about the opioids, but you know what I think is a bigger problem?
00:43:52This restriction of benzodiazepines.
00:43:54Okay?
00:43:56It turns out, and doctors have known this since the problem from cocktail in the days
00:44:01of laudanum, alcohol and Valium are chemically very much related.
00:44:05They act in the body the very same to relieve pain.
00:44:10And you've got to have something that does what technically is called a gamma-beta-butyric
00:44:15acid surrogate or triggering mechanism, meaning there are these spots in the brine called
00:44:22benzodiazepines or gamma receptors.
00:44:26If you don't trigger those things along with the opioid receptor, you're not going to get
00:44:30much pain relief.
00:44:32Now, they have scared doctors into not prescribing even a 2-milligram Valium for that.
00:44:38You can't get Xanax hardly anywhere anymore.
00:44:41Lorazepam is frowned upon.
00:44:43They absolutely don't want to give Halcyon for sleep.
00:44:46They have pejoratized.
00:44:49They have absolutely denigrated benzodiazepine unmercifully.
00:44:54These drugs have been around since the 1960s.
00:44:58And if you want really good pain relief, you're going to have to take a benzodiazepine and
00:45:03an opioid.
00:45:04Okay?
00:45:05Nobody wants to hear it.
00:45:06Everybody says you shouldn't prescribe it, but if you've got severe pain, you're going
00:45:12to have to have it.
00:45:13And I'll tell you what else you're going to have to have it.
00:45:15We've known this for a long time.
00:45:17To get good quality of care for terrible pain, you also have to have what's called a dopamine
00:45:23agonist or a dopamine surrogate.
00:45:27And that means you're going to have to take a drug like Adderall is the most popular one
00:45:31today, and of course, they're out of supply.
00:45:34Ritalin is another one that works pretty good on those, but so does dextroamphetamine.
00:45:39Even caffeine is not a bad actor.
00:45:44If you can't get it for Adderall, at least try half a dozen cups of coffee a day.
00:45:48That'll help you a little bit.
00:45:50So anyway, these are all things that stimulate this receptor.
00:45:54Bottom line is, and this may sound a little complex, but we know there are these triggering
00:46:01points in the brain, and the three big ones are opioid receptors, dopamine receptors,
00:46:09and GABA receptors.
00:46:10And you've got to trigger all three simultaneously to get good pain relief.
00:46:16Now, let me tell you the next pet peeve I have.
00:46:21I've got a copy sitting on my desk of the 1956 Merck manual, and what does it say?
00:46:29I love the statement.
00:46:31It says, if you can't get pain relief with methadone or morphine or oxycodone or hydrocodone,
00:46:40you need an injectable opioid.
00:46:42Do you know that today, trying to get doctors and patients to accept injectable opioids
00:46:49has gotten to be almost impossible, but yet they want pain relief.
00:46:56Oral opioids are very inefficient biologic compounds.
00:47:01You can't predict what they're going to do.
00:47:03You can't predict how often they're going to work or how well they're going to work.
00:47:06That's because when you swallow an opioid, you may lose 30 to 50% of it in your feces.
00:47:14You just don't know how much it's going to get in your system.
00:47:17That's why the pharmaceutical industry is trying to bring about patches and medicines
00:47:21to put under your tongue or on your cheek, and those are very good.
00:47:25But there's still no substitute for an old-fashioned injection or suppository.
00:47:32You know, the suppositories are almost off the market, but during most of my career,
00:47:38for pain flares and what have you, you used an opioid suppository or an injection.
00:47:46Now, today, my favorite injection is a new one.
00:47:51The drug's not new, but they now make what's called a micro-dose hydromorphone.
00:47:57That's not audit.
00:47:58And there's a company in Florida called Anazoa that makes this compound,
00:48:04and you use an insulin syringe, and you literally take a 10th of a cc to get relief.
00:48:13And on top of that, you can keep your doses down under the government level of 90 milligrams.
00:48:19I'm trying to get doctors and people to understand that the best pain relief,
00:48:24the safest and the least abusable on the street,
00:48:27they don't want that diavonin out there on the street because it's a micro-dosage.
00:48:33I've never even seen it used on the streets, but that's the very best pain relief.
00:48:38And let me say one other thing.
00:48:40In my opinion, the worst pain in patients I see today,
00:48:45it wasn't the case years ago, are people with neck problems.
00:48:49People who have discs in their necks that won't go away,
00:48:53and if they've got arachnoiditis in their neck, that's real pain.
00:48:58And you're not going to relieve that except with injectable dilaudid, in my opinion.
00:49:03I haven't had any luck with anything else, including fentanyl patches,
00:49:07including implanted morphine pumps, okay?
00:49:10So I'm on the warpath to educate people about micro-dose hydromorphone.
00:49:17Now, let me give you another surprise.
00:49:21Some of you have heard me say that if you can't get the opioids you need,
00:49:26at least get what your doctor or your nurse practitioner will give you
00:49:29in your local community, and then add something to it.
00:49:34Now, the one that has saved thousands of people is Kratom.
00:49:38Kratom is the one non-prescription opioid or opioid-like drug
00:49:43that is out there that you can buy without a prescription.
00:49:47In some states in this country, you can drive down the street,
00:49:49and you can go in there, and you can buy CBD or marijuana products
00:49:52and Kratom at the same time.
00:49:54On my way over here to do this podcast, I saw a new store right here in my hometown,
00:49:58or my town, that has both Kratom and CBD products.
00:50:04Okay, yeah, take advantage of it, but guess what?
00:50:07I have just now gotten some exhilarated letters by a number of people
00:50:13who have now found that some of the people who sell Kratom are selling an injectable.
00:50:20They have an extract of Kratom, and they're getting pain relief
00:50:24equal to morphine and dilaudid, okay?
00:50:28And it's non-prescription.
00:50:31Everybody who can't get enough pain relief better start checking into Kratom
00:50:34and also the injectable forms out there.
00:50:37And apparently, the federal government is allowing that to be used, okay?
00:50:43Dr. Tennant, if you don't mind,
00:50:47is that with the microdoses of the hydromorphone and the Kratom,
00:50:54is that subcutaneously or is that intravenously?
00:50:58Subcutaneously.
00:50:59It's actually infradermal.
00:51:01Okay, it's actually infradermal almost.
00:51:05It uses an insulin syringe, quarter-inch, okay?
00:51:08Micro dosage, okay?
00:51:10Doesn't hardly hurt.
00:51:12Anyway, I wanted to make you aware.
00:51:15Also, I will try to bring here each session anything that's new out there.
00:51:21At this point, there is a new herbal product
00:51:26that some people are claiming as good as morphine.
00:51:29I don't know, but you've heard of the drug clonidine.
00:51:32This is clonidine, C-O-N-O-L-I-D-I-N-E.
00:51:38Some people are claiming that that's a herbal product that's very, very potent.
00:51:43And we could use it.
00:51:44I mean, other non-prescription pain relievers,
00:51:46the best one out there is PEA, it's very popular.
00:51:50That's palmitoyethanolamide, that's a natural pain reliever.
00:51:57And there's some others out there that are certainly being used.
00:52:02In my time left, I want to bring you up to date a little bit on Epstein-Barr
00:52:09and on the peptides.
00:52:11In each session, I'll try to update you on those things.
00:52:15It turns out that the Epstein-Barr virus doesn't really suppress very well
00:52:20with the antivirals, but it does with a lot of other things.
00:52:24Interesting, okay?
00:52:26Now, the way the Epstein-Barr virus works is this.
00:52:28It lives in your lymphocytes, which floats around in your blood.
00:52:32That's its main normal place.
00:52:35All of us have it.
00:52:37That's just a natural parasite.
00:52:39It might shock you, but the body carries about 200 parasites, okay?
00:52:44Now, let me explain to you how parasites work.
00:52:47Anybody know what bad breath is?
00:52:50Sure you do.
00:52:51What's bad breath?
00:52:52Bad breath is when you haven't brushed your teeth for a while or eaten something
00:52:57bad, but if you don't do anything, it starts to smell, doesn't it?
00:53:02You get uncomfortable with it.
00:53:03Why?
00:53:04All those parasites that like to live in your gums and your mouth and your saliva
00:53:08start growing.
00:53:10So you got to go suppress them.
00:53:12So you're going to go brush your teeth, get a little mouthwash, flush it out.
00:53:16You smell better until later on in the day or the next day.
00:53:21But it's an easy, simple to understand situation on how parasites in the body
00:53:27work, okay?
00:53:29In other words, you have to recurrently flush out, suppress down, clean out,
00:53:36or beat up those parasites in your mouth, okay?
00:53:40Now, it turns out you got to do the same thing with EBV, with Epstein-Barr, okay?
00:53:46Epstein-Barr is actually pretty easy to suppress.
00:53:50If you eat a good diet of protein, vitamins, minerals, the chances are you're
00:53:57going to do pretty well in suppressing it.
00:54:00It's now been shown a lot of things suppress it.
00:54:03My favorite is plain old vitamin C, a dose of 2,000 to 4,000 milligrams a day is a
00:54:10good dosage for somebody with intractable pain.
00:54:12That may be all you need to kind of control your Epstein-Barr virus.
00:54:17There's a lot of good products coming on the market here.
00:54:19Lysine is an old amino acid.
00:54:21It does suppress the virus pretty well.
00:54:24Selenium is a mineral that does.
00:54:27Magnesium probably does.
00:54:30The most popular agent out there is monolaurin along with the contained lysine.
00:54:38That seems to be quite a good one.
00:54:39Bottom line is, there's a lot of publications coming out talking about different
00:54:44herbal products that will suppress the EBV virus.
00:54:48And I think they're absolutely correct.
00:54:50Okay?
00:54:51We've now got a lot of laboratory testing, laboratory test again, where the antibody
00:54:57levels have come down to the Epstein-Barr virus in our three-component protocol that
00:55:01we recommend for arachnoiditis.
00:55:04That protocol has got enough stuff in it and it will bring down the Epstein-Barr
00:55:08virus pretty well and keep you protected.
00:55:11Remember, it's not the cause of your problem, but it will make it worse.
00:55:15And so you have to know that you've got to suppress those parasites at all times.
00:55:20Now, to close out, I want to talk about the peptides.
00:55:24The peptides are the latest game changer, if you will.
00:55:29And we're starting to figure out better how to use them and which ones to start with.
00:55:35Okay?
00:55:37And we're also starting to understand that there are certain hormones that you can
00:55:40take and certain other supplements that make the peptides work better.
00:55:45And they all make pretty good sense.
00:55:47So I'll give you the latest update on these things.
00:55:50First off, there's about 60 different peptides being sold on the commercial market.
00:55:57Now, these are all non-prescription.
00:55:59And before you embark upon this, try to find out, if you're interested in a certain
00:56:04peptide, what they're using it for.
00:56:07Now, the people using the peptides primarily are your bodybuilders and your
00:56:12people in sports.
00:56:14Nothing wrong with that.
00:56:15But if they can build up their muscles to lift better, weight, look better at the
00:56:20contest, ride their bike farther or run faster, hey, we want to hear about it
00:56:26because they're making their tissues work better.
00:56:28Okay?
00:56:30And so we now are narrowing down to where it looks like there are three, maybe four
00:56:37of the 60 peptides that can help an intractable pain patient.
00:56:42And the first one you want to try is KPV.
00:56:45Okay?
00:56:46KPV.
00:56:47Now, you can get it by injectable or you can get it as a spray.
00:56:52KPV stands for three...I don't know why they call it KPV because it's really
00:56:57lysine, valine, and proline.
00:56:59So I don't know why they didn't call it LPV.
00:57:02But nonetheless, KPV, that's the one to start with.
00:57:06Now, why?
00:57:08That has a primary effect of pain relief.
00:57:12It activates your endorphins and it also activates some other neurochemicals
00:57:18in the brain.
00:57:19And so I highly recommend you try it.
00:57:22I do have a suggestion on how to get started.
00:57:26And anybody who's interested to get it in writing, write to Jamie or to the
00:57:31Tenet Foundation, we'll send you what we're recommending.
00:57:34First off, whether you're trying the injectable KPV or the spray,
00:57:39I recommend you try it for five days in a row.
00:57:42Five days in a row.
00:57:44And then stop and say, okay, what's it doing for me?
00:57:47I got better energy, better pain relief, better sleep, my mood better,
00:57:52am I more motivated?
00:57:54Has anything positive happened to me?
00:57:56If you can say yes, then switch over to using it about three times a week.
00:58:01Okay?
00:58:02Now, we've got some people that get so much pain relief from it,
00:58:05they just got to use it daily.
00:58:06If you have to, you have to.
00:58:08But peptides are like almost all these drugs.
00:58:11You don't want to use them every day, otherwise you'll get tolerant to them
00:58:16and they quit working.
00:58:17So if you can go every other day on the KPV or three times a week,
00:58:22that's what you want to do.
00:58:23And as far as we can see, you can take it for life.
00:58:26Okay?
00:58:27Now, there are three other peptides that pain patients are trying out.
00:58:32We don't have a lot of information yet.
00:58:35The other one that they like is the BPC-157.
00:58:39It does have some side effects and that bothers some people.
00:58:44You have one called thymus and beta 500.
00:58:48That's turning out to be a pretty good one and had no side effects.
00:58:52So thymus and beta maybe right up there with KPV is the one you want to try next.
00:58:57Now, the ARA-290, we don't know how that's going to work out
00:59:01because that's one you got to take by injection almost every day for 30 days
00:59:06to even see if it works.
00:59:08So I don't know how practical it's going to be.
00:59:12People start off with it, but then they quit it.
00:59:14So at this time, we have no good data to recommend it.
00:59:18The manufacturers who make the peptides say it works, I don't know at this point in time.
00:59:24Maybe, maybe not.
00:59:25But anyway, we do have the three, KPV, BPC-157, and the thymus and beta 500.
00:59:33Those three look like winners and that they really should become part of the protocol.
00:59:38It fits right in with the three-component protocol.
00:59:42It'll fit one of the three components, if not more than that.
00:59:45So that's, I know it's been a long lecture.
00:59:48We've covered a lot of detailed stuff and I'm sure some of the stuff may not sit well
00:59:53with you, but I'll give it my best shot.
00:59:56Now, next week, I'm going to have my associate on, Dr. Jay Purcelli.
01:00:00Our foundation has been helping Jay Purcelli, he's an osteopath,
01:00:05figure out how to get people who are on high-dose opioids to be able to have a good,
01:00:11comfortable life and not go above the federal level of 90 milligrams.
01:00:15And he's going to tell us what he's been doing as a general practitioner to make that happen.
01:00:21So I've got him coming on next week and we hope to have some other good people coming
01:00:25on more as we move forward.
01:00:27Jamie, thanks again.
01:00:29We'll carry on next time.
01:00:32Let's check everybody's questions.
01:00:34Glad to be back with you.
01:00:36But again, here's our goal.
01:00:38For those 5% of people or pain patients who are suffering, can't get treatment or can't get
01:00:45right treatment, we hope to better everybody right along and make it happen
01:00:49throughout the country.