(Adnkronos) - In questo numero:
Dona rene a uno sconosciuto e salva 3 pazienti: la storia
Neuroscienze, Lundbeck Italia festeggia 30 anni di attività con l’evento istituzionale ‘La salute parte dal cervello’
Prevenzione andrologica e nuove sfide nel convegno della Sia
Ail celebra 55 anni di impegno con Papa Francesco: "Insieme illuminiamo il futuro"
Da AstraZeneca nuove frontiere di trattamento in oncoematologia
Essere genitori oggi, un tema economico e culturale
Sma, l'importanza dello screening neonatale e dei nuovi medicinali per contrastare la patologia
L’impegno di Siaarti contro il dolore cronico
Novartis promuove media tutorial sull’Emoglobinuria parossistica notturna
“Allenarsi senza soffrire è possibile”. Ad affermarlo la chinesiologa Federica Accio
Siti presenta a Roma nuovo calendario vaccinale per la vita
Un talk di esperti sul tema del self-care come risorsa per cittadini e Ssn
‘Lo stesso fuoco’: in onda la webserie per sensibilizzare sui rischi legati all’herpes zoster
Anche gli animali in libertà si 'sbronzano', dagli uccelli alle scimmie così assumono alcol
Dona rene a uno sconosciuto e salva 3 pazienti: la storia
Neuroscienze, Lundbeck Italia festeggia 30 anni di attività con l’evento istituzionale ‘La salute parte dal cervello’
Prevenzione andrologica e nuove sfide nel convegno della Sia
Ail celebra 55 anni di impegno con Papa Francesco: "Insieme illuminiamo il futuro"
Da AstraZeneca nuove frontiere di trattamento in oncoematologia
Essere genitori oggi, un tema economico e culturale
Sma, l'importanza dello screening neonatale e dei nuovi medicinali per contrastare la patologia
L’impegno di Siaarti contro il dolore cronico
Novartis promuove media tutorial sull’Emoglobinuria parossistica notturna
“Allenarsi senza soffrire è possibile”. Ad affermarlo la chinesiologa Federica Accio
Siti presenta a Roma nuovo calendario vaccinale per la vita
Un talk di esperti sul tema del self-care come risorsa per cittadini e Ssn
‘Lo stesso fuoco’: in onda la webserie per sensibilizzare sui rischi legati all’herpes zoster
Anche gli animali in libertà si 'sbronzano', dagli uccelli alle scimmie così assumono alcol
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NewsTranscript
00:00In this issue, Donna Renea, a stranger and savior to three patients, the story.
00:15Neurosciences, Lundbeck, Italy, celebrates 30 years of activity with the institutional event
00:21Health starts from the brain. Andrological prevention and new challenges at the convention of the CIA.
00:26Hale celebrates 55 years of commitment with Pope Francis. Together we illuminate the future.
00:33From AstraZeneca, new frontiers of treatment and non-comatology. And again, being parents today,
00:40an economic and cultural issue. SMA, the importance of neonatal screening and new
00:46medicines to counteract the pathology. The commitment of C-Arti against chronic pain.
00:52Novartis promotes a media tutorial on paroxysmal hemoglobinuria at night.
00:57Training without suffering is possible, as stated by the kinesiologist Federica Accio.
01:03SITI presents a new vaccine calendar for life in Rome. A talk by experts on the subject of self-care
01:10as a resource for citizens and the national health service. The same fire floods the webseries to
01:17sensitize on the risks related to herpes zoster. Even animals in freedom
01:23get tanned. From birds to monkeys, so they take in alcohol.
01:34A man donated one of his two kidneys live, entrusting it to the national transplant network,
01:38which used it to start a chain of donations between cross-plants,
01:42between incompatible couples, which led to a normal life for three patients,
01:46between Padova, L'Aquila and Bologna. It is the so-called Samaritan donation,
01:50which takes place when a person in perfect health conditions
01:53undergoes a kidney transplant to be given not to a family member or friend,
01:57but to a completely unknown person on the waiting list for the transplant.
02:01All in a totally free and anonymous format. In total, 110 health workers were involved,
02:07including doctors, nurses, psychologists, biologists, staff of the National Transplant Center
02:12and the regional coordinators of Veneto, Abruzzo and Emilia Romagna.
02:15The Samaritan donor entrusted himself to the Reni Pancreas Transplant Center of the hospital in Padova
02:20and before being admitted to the donation program, he had to face a rigorous clinical evaluation
02:25clinical, immunological and psychological heater, as defined by the current national protocol,
02:30which allowed him to reach the definitive free way of the tribunal competent territorially,
02:35which authorized the transplant from a living person, ensuring freedom and awareness of the decision.
02:40The procedure of extraction, evidenced at the National Transplant Center,
02:43does not involve particular risks for those who decide to undergo it
02:47and once performed, the donor can return to a perfectly normal life.
02:51Having obtained the magistrate's permission, the National Transplant Center,
02:54directed by Giuseppe Feltrin, accepted the donation of the organ,
02:58using it to activate a series of transplants with chains between couples and donor and recipient,
03:02among them incompatible.
03:04The Samaritan kidney has been assigned to a patient in care
03:07at the Transplant Center of the hospital San Salvatore dell'Aquila.
03:11A relative of the Aquilano recipient, incompatible with the latter,
03:14has donated a kidney that has been assigned to a patient of the Reni Pancreas Transplant Center
03:19of the Sant'Orsola polyclinic in Bologna.
03:21Also in this case, a relative of the transplanted has donated a kidney
03:24that has been assigned to a patient enrolled in the ordinary waiting list
03:27at the Padova Transplant Center.
03:29In this way, the chain of donations closed with the realization of three transplants,
03:33all perfectly successful.
03:35This last Samaritan donor was the ninth to make this choice in Italy since 2015,
03:40the first since 2019.
03:42In total, thanks to the new Samaritan donations,
03:4529 kidney transplants have been made,
03:47with the involvement in the different chains of transplants
03:50of 21 couples, donor and recipient.
04:00Trace the path of the evolution of neurosciences in the last 30 years
04:04and promote a transversal and multi-stakeholder dialogue on the health of the brain.
04:08This is the goal of the institutional event entitled
04:11Health starts from the brain, neurosciences in Italy, past, present and future.
04:16Organized by the Danish biopharmaceutical company specialized in neurosciences,
04:20Lundbeck Italy, to celebrate its 30th anniversary of activity and commitment in our country.
04:25I believe that the subsequent progress will be especially from psychiatry.
04:31We have a great need to improve the current psychiatry,
04:36those acts we have seen of murderers, etc.
04:39One wonders, as the English say, if they are bad people or mad people.
04:46And a prevention in this sense would be essential for society.
04:50Many individual challenges faced by the Technical Board for Mental Health of the Ministry of Health.
04:56A series of hearings to listen,
04:59to give space to all the people who work in this field
05:03and have particular needs that we have collected
05:07and that we will try to find a concrete breakthrough
05:12in the national action plan on mental health
05:15that we are preparing and that we hope in the coming months of 2025
05:21you will find its definitive publication.
05:25The challenges are different because they concern the age of evolution,
05:28they concern the stigma, they concern the organizational models
05:33such as the safety, for example, of the operators
05:36and of the patients who attend the mental health centers or the emergency services.
05:42The president of the Italian Society of Neurology illustrates the challenges of brain health
05:47in the perspective of One Brain, One Health.
05:49The challenges are to understand how everything is united
05:53but at the same time we must identify for each condition, for each disease
05:59what are the real mechanisms and act on them.
06:03We can certainly act through prevention,
06:06which we are strongly committed to,
06:09but also in the development of drugs or treatments.
06:13Not all treatments are pharmacological, it must be said.
06:17I must say that Elon Musk, to name one,
06:19has opened a new frontier, that of Neuralink,
06:24but that of the stimulators and the interface between the brain and artificial intelligence.
06:30I believe that this is still a boundary to explore
06:34and I believe that in the coming years there will be very strong news in this area.
06:40For Lumbek, health starts from the brain,
06:42for this reason it is important to have therapeutic options
06:44that can improve the life of those affected by neurological and psychiatric pathologies.
06:48We are not satisfied only with therapeutic solutions,
06:52but our goal is to be a partner of the institutions,
06:57of the scientific class and of the patients' associations
06:59to also identify projects that can focus
07:03on people who suffer from these pathologies and their family or caregivers.
07:10The S3 Convention on Health and Sexual Health, SIA, was held in Milan.
07:14The S3 Convention on Health and Sexual Health, SIA, was held in Milan,
07:18which celebrates the almost 50 years of activity of SIA,
07:21an Italian andrology company.
07:23It was also an opportunity to talk about the importance of prevention.
07:27Today we are talking about this prevention campaign
07:29that has been carried out throughout 2023 until the beginning of 2024
07:35and above all very important for the younger generations,
07:39so the 14, 15, 16, up to 18 years old,
07:44that we must check and tell what are the appropriate lifestyles
07:50that these young people must follow
07:53to avoid having problems and diseases as elderly people.
07:57The main national experts have made a balance
08:00on the successes of the previous prevention campaigns
08:03and the point on the challenges of andrological prevention at 360 degrees,
08:07which embraces all age groups.
08:10Preventing something today means not being in front of so-called pathological conditions tomorrow,
08:16that is, something that does not work,
08:17on which we will have to deal with expenses
08:21and also with problems for the individual and especially for society.
08:25Technology then pushes a reflection
08:28on what will be the role of the andrologist in the future.
08:31We will take into account what has been done and what we have to do,
08:36also in light of how the relationship is changing,
08:40both medical and patient, in light of new technologies.
08:44I am referring to Dr. Google, Professor GPT,
08:48as it is now called,
08:49to new technologies based on artificial intelligence.
08:52And therefore a reflection to also ask
08:56what the andrologist of the third millennium will have to be,
09:00how he will have to relate to the new patient,
09:03this new pathology that is spreading a bit cyber-chondriacally,
09:11and in which the experts are trying to clarify.
09:18During the conference, the investigation carried out in collaboration with the University of Ulm in Milan
09:23and directed to young Italians was also presented.
09:25The University of Ulm, I am in charge of the SIA,
09:28of the Italian Society of Andrology,
09:29has done this research precisely to understand
09:31what are the cultural blocks that young Italian males have
09:37regarding andrological prevention and andrological cures.
09:42There are cultural blocks,
09:44this is what our research has shown,
09:46there are various causes
09:48that have to do with, I would say, the male culture of a nation,
09:53but doing research also means clarifying these causes
09:58and therefore finding possible solutions to solve these blocks.
10:06The first care we need in the disease is the closeness full of compassion and tenderness.
10:12With these words, Pope Francis welcomed over 3,000 volunteers,
10:15patients, relatives, doctors, researchers and health workers of the ILE
10:20in the Paolo VI Hall of the Vatican City
10:22for a private audience on the occasion of the 55th anniversary of the organization.
10:28The meeting with the Holy Father represented a moment of great spiritual intensity and sharing,
10:33celebrating the role of the Italian Association against Leucemias, Lymphomas and Mieloma
10:38as a reference point for hematological patients and their families.
10:42The ILE community, led by the National President Giuseppe Toro,
10:45wanted to reaffirm the value of solidarity, care and welcome
10:49that have always characterized the association.
10:52Today we are honored, we are honored with this opportunity
10:55that the Holy Father gives us to celebrate our 55th anniversary
11:00in such an important way, so full of spirituality, full of warmth
11:08and above all to realize this commitment of ours,
11:14which is above all projected for the future.
11:16There is still a lot to do.
11:18Leucemic diseases are cured in a very positive way today,
11:26more than 70% are solved, but there is still a lot to do.
11:31The symbol of the event was the candle, the emblem of hope and light in the dark,
11:35accompanied by the message together we illuminate the future.
11:39This slogan summarizes the commitment of the ILE in supporting patients,
11:42financing scientific research and raising public opinion
11:46on the fight against blood tumors.
11:48Pope Francis stressed the importance of putting the sick person at the center,
11:52offering light and hope through closeness and listening.
11:56The meeting ended with a symbolic representation in Piazza San Pietro,
12:00where the participants formed the number 55 ILE,
12:04using red cardboard to celebrate the association's past
12:08and look forward to the future.
12:09ILE, which has been supporting patients and families for 55 years
12:12along the difficult path of the disease,
12:15renews its commitment to be a beacon of hope.
12:18We can say that a volunteer looks deep into the person,
12:23because we cure the whole person, not just the disease itself.
12:27Seen objectively, the tumor, any leukemia, yes, they are very serious diseases,
12:34but they are above all to cure the person, they are above all to live the experience.
12:40The patient must not be left alone, the patient must be accompanied.
12:44And this is what we do today, it is the hope of the Gospel that becomes flesh.
12:54With the press conference, Blood Tumors and the New Frontiers of Treatment
12:58by the Congress of the American Society of Hematology,
13:00AstraZeneca illustrated in Milan the results of two important clinical studies
13:04presented at the ASH 2024 Congress,
13:07the 66th Congress of the American Society of Hematology.
13:11Signed by the Best of ASH, the Phase III Amplify clinical study
13:15highlights the potential of a new therapeutic frontier
13:18in the treatment of chronic lymphatic leukemia.
13:21The study examines the effectiveness of acalabrutinib and venetoclax
13:24as the first fixed-duration oral regimen of a secondary-generation
13:28Bruton inclinatory thyroid inhibitor in the treatment of oncological pathology.
13:32The study has shown that the arms we have with acalabrutinib and venetoclax
13:37have a better survival free of progression
13:41compared to immunochemotherapy.
13:42In fact, the survival free of disease has been achieved with immunochemotherapy
13:48and while three years ago, with acalabrutinib and venetoclax,
13:52it was 77% or 83% when we combined the monoclonal antibody.
13:58This is seen above all in patients at higher risk
14:01with non-mutated immunoglobulin characteristics on the surface,
14:05who have a slightly cheerful disease compared to mutated patients
14:11and it is a bit early to talk about survival,
14:13but we also have a better survival of acalabrutinib and venetoclax
14:17compared to immunochemotherapy.
14:21At the ASH Congress, the updated results of the ECHO study on acalabrutinib
14:26in combination with chemoimmunotherapy
14:28in the treatment of the first line of patients over 65 with lymphoma mantlellare were also presented.
14:32The study has brought very satisfactory results,
14:38in the sense that the innovative therapy associated with chemoimmunotherapy with acalabrutinib
14:43has shown an improvement in patients in the first line,
14:48therefore not previously treated,
14:50both in the progression free of disease
14:54and with a strong trend also in relation to global survival.
14:58Therefore, this association, which has also been little toxic
15:03compared to what could have been expected from a similar combination of several drugs,
15:09will likely become a new standard of therapy in lymphoma mantlellare
15:16with 65 years or older, therefore adult-elderly,
15:20and will represent a new further step
15:24in the improvement of global survival in this important hematological pathology.
15:31But the commitment of AstraZeneca in the hematological field is even greater.
15:34We have entered this area, which is super-specialistic,
15:38therefore really very complex,
15:40and in this area we want to continue to bring innovation and research,
15:44and we are doing this with more than 100 studies in oncology in Italy,
15:48almost 10% are in hematology and, above all, they continue to grow over the years,
15:53so we don't stop here, we have new molecules
15:56and, above all, we want to go to new pathologies
15:59where we want to bring our contribution to take steps forward
16:03and we hope to have other successes in this field.
16:11Turn on the reflectors on the support for parenting
16:14through some fundamental guidelines,
16:17economic policy, education and prevention to promote fertility,
16:21techniques to overcome infertility
16:23and the implementation of a corporate welfare oriented to favor coherent life choices
16:28with an increase in birth rate.
16:29This is the goal of the new meeting of ADN Kronos Question & Answer Demographic
16:34carried out in partnership with Merck.
16:36We are talking about sustainability.
16:38There is no sustainability when there are no children to support the future.
16:43In Italy, every year there is a reduction in the number of children we have.
16:48In 2023, less than 400,000 children were born.
16:523.4% less than in 2022.
16:5525% less than 10 years ago.
16:59Is it an economic issue?
17:00It is an economic issue, but not only.
17:03There is a lack of education.
17:05We did a survey where 72% of young people in Europe
17:10know nothing about the ovarian reserve.
17:1562% are not aware of the treatment to help fertility.
17:21We must confront this level of education.
17:24Merck, as a leading company in fertility,
17:28the treatment of fertility was born with Merck more than 50 years ago here in Italy.
17:33We need to share this education
17:37to confront this problem that we have in Italy and throughout Europe.
17:40This is the first commitment we have.
17:42According to gynecologist Cola Curci,
17:44young people do not think about the future as much as they do about the present
17:47and, as a result, they are little projected to parenthood.
17:50Parenthood means taking on a series of commitments
17:54that interfere with their individual fulfilment.
17:58They are extremely focused on their individual fulfilment
18:03and we should be able to make parenthood
18:08a factor that certainly facilitates their personal fulfilment.
18:13The world of work plays a central role
18:16to counter the demographic ice and to face a society that is aging.
18:20A greater confidence in the future,
18:23greater stability and tranquillity in the management of the work-life balance,
18:29greater agility, better conditions to manage parenthood and work contextually
18:35are certainly factors that can help
18:40to make the choice of parenthood more aware and more serene
18:45and also to maintain solid, qualified and stable work paths in time.
18:52And this is true for mom and dad, no matter what.
19:01Spinal muscular atrophy, SMA,
19:02is a neuromuscular pathology that affects about 1 in every 12,000 people.
19:05Before 2017, when new drugs and the possibility of a neonatal screening
19:10brought more than 90% to the probability of survival,
19:13it was the first cause of death in childhood in Forma 1, the most serious.
19:16From the advent of drugs and treatments,
19:19I like to talk about a real Copernican revolution or a SMA 3.0.
19:24Children with Forma 1 no longer die
19:28and I believe that this is really the great revolution,
19:31the great victory that the scientific community
19:35and the family association have achieved in recent years.
19:38But then the arrival of newborn screening,
19:41and therefore of neonatal screening,
19:43has still radically and definitively subverted this situation.
19:49You have the opportunity to offer something to two young parents
19:52who have diagnosed a disease of this kind
19:55and above all to give them a completely different quality of life
19:59compared to what it was six or seven years ago.
20:03On the other hand, of course, it's a bit like breaking a castle.
20:08We, let's say, break what is a castle that in nine months
20:12these two young parents have built
20:15and therefore, let's say, it is certainly a strong impact,
20:18a very strong emotional impact that must be managed
20:21and therefore we also need the help of psychological support.
20:26We try to communicate the diagnosis together with the geneticist,
20:30but then also together with a psychological support
20:33that follows the family along the way and also in the therapeutic choice.
20:38There are many experiments in new pharmacies
20:40and the ways of administering those already existing,
20:42such as, for example, the administration for midollo
20:44instead of the one in Vienna-Venosa.
20:46Genetic therapy, which at this time was only available
20:50for endovena administration for children of relatively small age and weight,
20:57is in an experimental phase
20:59to see the possibility of being able to adopt the same therapy
21:03but administering it for entratecane,
21:06that is, directly in the midollo.
21:08This would allow to give smaller doses
21:12compared to the very large doses that should be given
21:14for a very large child or for an adult
21:16where endovenous administration was carried out.
21:20There are also other pharmacies in experimentation at the moment
21:25which are different pharmacies.
21:27The most obvious example is that of myostatin inhibitors,
21:31that is, drugs that, if administered, would favor muscle growth,
21:37where instead the mechanism of the pathology
21:39is to make the muscle a little smaller.
21:41In Italy, we have been instituting for several years
21:45a registry called ISMAR,
21:47part of an international registry
21:49that was then expanded in Italy
21:51to cover the entire Italian network
21:54of all the centers that are recognized by the region
21:57as prescription centers for spinal muscular atrophy.
21:59Just recently, this large registry allowed us
22:02to go and see what has happened in Italy since 2016,
22:06that is, since the year the first drug was available for these children.
22:11And it is beautiful to see that while in the past,
22:14before the arrival of drugs,
22:16we had that only 8% of children survived over two years,
22:20now we have a percentage of children treated
22:23that is more than 90% not only two years old,
22:26but some of these children are already 7-8 years old.
22:33On October 22, on the first day of activity,
22:35there were more than a thousand calls
22:37reached the free number 800-624-244
22:42dedicated to those suffering from chronic pain.
22:45From the other end of the phone,
22:46the experts of SIARTI,
22:48the Italian Association of Anesthesia,
22:50Analgesia, Reanimation and Intensive Therapy,
22:53the commitment of SIARTI
22:54does not decline only through the green number,
22:57but also through a series of activities.
22:59SIARTI, as a scientific society in pain therapy,
23:03has several key points to make this discipline grow.
23:08The first is to promote good clinical practices or guidelines
23:12to give safety to professionals
23:14in the execution of their daily work.
23:17The second, of course, is training.
23:20The training of anesthesiologists and reanimators
23:23when they are in specialization school,
23:25but also in their daily work,
23:29if they want to dedicate themselves later
23:31also to pain therapy
23:33or to recognize patients who need it.
23:38Fundamental with these two first points
23:40is also the relationship with the institutions,
23:42first of all the Ministry of Health,
23:44but also the Institute Superior of Health
23:46or whoever wants to deal in a correct,
23:50scientific and punctual way with these issues.
23:54Only 8 out of 100 patients go to the dedicated centers.
23:58SIARTI is the only society that has analgesia in its name
24:05and not only that, the motto of SIARTI
24:07is Pro Vita Contra Dolorem Semper,
24:10so we have it in our DNA
24:12to be pain therapists
24:14and to take care of the patient.
24:16It is obvious that we need pathways,
24:19we need a functioning network,
24:21we put all the skills,
24:24but it is necessary that the patient
24:26be directed early to the pain therapy center
24:31when this does not respond to the therapies that we expect
24:36and therefore I invite patients, but also doctors,
24:39to ask for information through our green number.
24:42There are 9.8 million Italians who suffer from chronic pain,
24:47an important number,
24:48an emblem of a serious problem in our country.
24:51We must focus on the two pillars
24:54on which a correct approach is founded
24:57in charge of the patient affected by chronic pain.
25:00The two pillars are the multi-modality of therapy,
25:04therapy is not just a drug,
25:06but it is a drug,
25:08psycho-emotional support
25:10and non-pharmacological techniques,
25:14including those invasive and invasive techniques
25:17that are more properly relevant
25:20to the discipline of anesthesia and resuscitation.
25:23The other pillar on which a correct approach
25:25to the therapy of chronic pain is founded
25:28is interdisciplinarity.
25:31This means that we cannot think
25:33of treating a patient affected by chronic pain
25:36only through a single professional approach.
25:39What is the cause of chronic pain?
25:43It affects men and women in equal measure,
25:45with symptoms of extremely variable severity.
25:48Although the pathology can develop at any age,
25:50it is often diagnosed in people of age
25:52between 30 and 40 years of age.
25:55It is hemoglobinuria paroxystica nocturna,
25:57a rare, chronic and serious blood disease
26:00that occurs when a part of the immune system,
26:02called the complement system,
26:04attacks the red blood cells,
26:06devoid of some regulatory proteins.
26:08It is estimated that in the world
26:09about 10-20 people out of a million are affected.
26:12This was discussed in the course of the media tutorial
26:14of Novartis Italy,
26:16entitled Hemoglobinuria Paroxystica Nocturna,
26:19towards a better control of the disease.
26:21The main symptoms are anemia.
26:25The patient therefore feels tired, tired,
26:28and this is most often the reason
26:30that leads him to the doctor.
26:32Other times the symptoms are particular,
26:37such as thrombotic events,
26:39and therefore the arrival is more dramatic,
26:42let's say, in quotes,
26:44to the emergency room by his own doctor,
26:46because it is the thrombotic event
26:47that led the patient to turn to the health care workers.
26:50Other times, even worse,
26:53there can be a picture of peripheral pancytopenia,
26:57that is, all the cell lines,
27:00red blood cells, white blood cells,
27:02platelets, are low,
27:04because in reality
27:05Hemoglobinuria Paroxystica Nocturna
27:07in that case is also associated
27:10with what we call middle-class aplasia.
27:13Thanks to scientific research,
27:15they are working on the therapeutic panorama,
27:17drugs capable of revolutionizing the standard of care.
27:20These drugs have reduced hemolysis,
27:23increased hemoglobin levels,
27:25therefore improved anemia,
27:26and, above all,
27:28lowered the risk of thrombosis in our patients,
27:30improving survival.
27:32They are now at the door of new treatments
27:35that, in addition to making the patient survive more,
27:38can have an improving effect
27:40also on their quality of life,
27:42because they are able to further increase
27:45hemoglobin values,
27:46also solve residual anemia
27:49linked to the incomplete functioning,
27:51let's say, of these C5 inhibitors,
27:54and therefore really allow
27:56the almost normalization of hemoglobin levels,
28:00and therefore of the quality of life of our patients.
28:02Novartis has been committed for more than 20 years
28:05in the field of hematological research.
28:07We know that today,
28:09with the available treatments,
28:11more than 80% of patients
28:16do not reach satisfactory fatigue levels,
28:21therefore they continue to manifest
28:23a level of constant fatigue,
28:25and 30% of patients
28:28still constantly need blood transfusions.
28:34The therapeutic proposal of Novartis
28:38is aimed at trying to fill
28:42these two important unmet needs,
28:45reducing fatigue on the one hand
28:48and blood transfusions on the other.
28:57Italians and physical activity
28:58do not exactly form a winning pair,
29:01even more so during Christmas holidays,
29:03when the must-haves are rest and food.
29:05For the most part, if you think about it,
29:07as emerged from a recent survey
29:08of the Institute for Health,
29:10Italians are essentially lazy.
29:12The physically active adults
29:14between 18 and 69 years old
29:15are in fact just under half,
29:17less than 1 in 4 are partially,
29:19while almost 3 in 10 are sedentary.
29:22The problem increases with age,
29:24and walks and house care
29:26are the favorite physical activities.
29:28On the other hand, however,
29:29as the Anglo-Saxon expression
29:31no pain, no gain,
29:33it would not be possible to achieve
29:34certain results without suffering,
29:36which leads many people to avoid it.
29:38Yet in its real meaning,
29:40this statement should represent
29:42a motivational motto,
29:43which should help people
29:44to find the right energy
29:46in the face of complex and tiring situations.
29:49To dissolve any uncertainty
29:50between these two interpretations
29:52come the suggestions of the Chinese psychologist
29:53Federica Accio,
29:54author of the books In Forma Con Fede
29:56and La Rivoluzione delle Quattro A,
29:58whose approach to well-being
29:59is based on moderation and awareness.
30:29And how can you motivate
30:56those who find it difficult
30:57to start a fitness path?
30:59Motivation is born from the awareness
31:03of being able to perform
31:04with serenity
31:06a physical exercise that will allow you
31:09to have great results
31:11both in terms of aesthetics,
31:13so less fat,
31:14more muscles without fatigue
31:16and psychological well-being,
31:19but also in terms of prevention.
31:22As you brush your teeth daily,
31:25you will do your gym.
31:28More muscles with the brain.
31:32But what role does physical activity play
31:33in health prevention and maintenance?
31:36The World Health Organization
31:38has scientifically clarified
31:42that exercise is a real preventive drug
31:46and a therapy of the human body's
31:48psychophysical well-being.
31:50It improves heart and lung function,
31:55improves the quality of our muscles
31:58and keeps us in a psychophysical
32:01and also emotional health.
32:05Because it relaxes us,
32:07because it brings us a feeling
32:10of mental lightness
32:13and allows us to be better
32:15with ourselves
32:17and consequently
32:18also with those around us.
32:29Based on the most recent scientific evidence
32:31written with the contribution
32:33of the Italian Society of Hygiene,
32:34Preventive Medicine and Public Health,
32:36the Italian Society of Pediatrics,
32:38the Italian Federation of Pediatric Doctors,
32:40the Italian Society of General Medicine
32:42of Primary Care
32:43and the Italian Federation of General Medicine Doctors,
32:46the 2025 edition of the Vaccination Calendar for Life
32:49presented in Rome by the EMPAM Foundation
32:51includes all vaccinations
32:53able to guarantee for each age group,
32:55from birth to adolescence,
32:57the promotion of an optimal state of health
32:59through prevention.
33:01It is extremely important
33:04to be able to vaccinate
33:05against all infectious pathologies
33:08that unfortunately persecute us
33:11throughout life
33:13with extremely different pathologies.
33:16The Vaccination Calendar,
33:18updated to the Calendar for Life,
33:21provides for all vaccinations
33:24that are now available in Italy
33:27and that are safe and effective
33:30against infectious pathologies.
33:32Infectious pathologies
33:34that unfortunately we have seen in recent years
33:37have not disappeared
33:38but together with antimicrobial resistance
33:41represent and will represent
33:43one of the main causes of disease
33:46in the coming years.
33:47Among the main novelties
33:49included in the new Vaccination Calendar for Life
33:51is the COVID-19 vaccine.
33:53The disease, in fact, has not yet disappeared
33:55and continues to be dangerous
33:57for the elderly and the fragile population.
33:59There is also the vaccination
34:01against the syncytial respiratory virus,
34:03currently in use in all Italian children
34:05and that is seeing a good adhesion.
34:07Then we have important calls
34:11for the adolescent vaccination
34:13against meningococcal B,
34:14which is the most important bug
34:17that affects the adolescent population
34:19in addition to the pediatric one.
34:21We have two new vaccines
34:23for the 15-20 valent premococcus
34:26that must be used
34:28guaranteeing coverage,
34:29in fact increasing it
34:30and doing it in the time provided.
34:33HPV is a new chapter
34:36that I pay attention to
34:38because today it seems unacceptable and absurd
34:41that just over half of Italian adolescents
34:46carry out this vaccination
34:47with a vaccination against serious forms of cancer
34:50and it is a vaccine that works virtually 100%.
34:53So we need to call for
34:54a higher adhesion to this vaccination.
35:01According to the World Health Organization,
35:04self-care means taking care of your health,
35:07preventing diseases,
35:09staying healthy,
35:10treating small disorders
35:12with or without the support
35:13of a health worker,
35:15such as a pharmacist.
35:17Self-care is talked about in the course of the talk,
35:19a resource for citizens
35:21and a national health service
35:23promoted by ADN Kronos.
35:24It is clear that,
35:26given that it is an extremely wide and varied world,
35:29if we look at the product categories
35:32that are part of the self-care world,
35:35we usually use an exception
35:37that includes everything that is a bank drug,
35:40so the drug that does not require a medical prescription,
35:43OTC,
35:44everything that is the world
35:46of food integrators, of supplements,
35:48and all that can be the solutions
35:51of products or services
35:52that take care of health,
35:55such as oral care products.
35:59If we use this perimeter,
36:01in Italy we are talking about a market
36:02of about 7.5 billion,
36:04so an important market,
36:06growing,
36:07and clearly it has taken more and more
36:10importance even after the pandemic.
36:13It is clear, however, that the value of self-care
36:17is a value that goes beyond
36:19the narrow economic value
36:21of the products,
36:22it has a broader value
36:24also in the social sphere,
36:27and it is a more complex value to assess.
36:31The President of the Federation of the Orders of Italian Pharmacists
36:34has illustrated the essential elements
36:36in the national prevention plan
36:38so that self-care becomes a real resource
36:41and the tools useful to the pharmacist
36:43to facilitate responsible self-medication.
36:45The first is certainly a work of communication
36:50to the patient, of information.
36:52Too often we live in an era
36:53in which the information is so redundant
36:55that it is almost asymmetrical
36:57to the patient's ability to choose
37:00and discern if the information he finds on the web
37:03is more or less correct for his family,
37:05for himself, for some of his loved ones.
37:08So we need, first of all,
37:09a strong campaign of awareness.
37:12Second, we need a training,
37:17also, in my opinion,
37:19in conjunction with the DM-77
37:22between doctors and pharmacists
37:24who can finally
37:26put themselves in a common set
37:28to assist the patient.
37:30And at this point,
37:33a lot of empathy
37:35to build that dialogue
37:38which is always fundamental in health,
37:39because you don't cure only with a drug,
37:42only with a self-medication drug,
37:44but you also cure with the approach,
37:46with the word, with the sensitivity
37:48towards those who are sick.
37:49In this context, it is therefore necessary
37:51to intervene on a health literacy
37:54of citizens through training.
37:57Also starting from schools,
37:58active involvement of communities,
38:00of health institutions,
38:03to create a culture linked to prevention.
38:06Because every euro invested in prevention
38:07is 7 euros invested,
38:09so we also work for a sustainability
38:12of our national health system
38:14to which we all belong,
38:15a universalist system,
38:17free, public, for all citizens,
38:19but clearly very fragile
38:22in the sustainability of its costs.
38:24And therefore, each of us must be a citizen
38:26responsible for their own health
38:28and also for the public health of our country.
38:36A web series to raise awareness
38:38on the risks related to the herpes zoster,
38:40also known as the San Antonio fire,
38:42and to spread awareness
38:43on this often underestimated pathology.
38:46It is the same fire that in eight episodes
38:48tells the stories of those who live
38:50with this pathology in different phases of life
38:52and different contexts,
38:54including that of comorbidity.
38:55We still need to inform.
38:57We have seen the facts
38:59from a socio-demoscopic survey this year
39:02that in fact only 9% of the population
39:06knows the real dangers
39:08and the real consequences of this pathology.
39:10Then, the web series is also an ideal language
39:14to explain the disease in a clear,
39:16non-alarming way
39:18and remind everyone
39:20the importance of always consulting
39:23with their doctor,
39:24even just to have more information.
39:27To restore a clear picture
39:29of the pathology and the risks it entails,
39:31the work done by the director
39:34and the actors together with the medical team was essential.
39:36Not only through the dialogues,
39:38but also on a visual level.
39:40Visually, because the production of the prostheses
39:43that we had to use during the shooting
39:46was also in the pre-production phase
39:50justly prepared
39:51to go and see the first phase of the herpes zoster
39:56up to the final phase of the herpes zoster
40:00on the character of Mario
40:01that you will see in the web series.
40:04Caused by the reactivation of the varicella virus,
40:06the herpes zoster affects the nervous structures
40:09and, if not recognized and treated,
40:10can lead to serious complications,
40:12invalidating and sometimes fatal,
40:14especially in the elderly
40:16and in the frail patients
40:17due to concomitant pathologies,
40:19as in the case of the protagonist of the series, Sophia,
40:22an oncological patient
40:23also affected by the herpes zoster.
40:25Being able to work on these issues
40:30while maintaining a positive tone
40:34and a way of creating the character,
40:41even real,
40:43created a sort of short circuit for me at the beginning.
40:49And then I think I found a way
40:52and I hope that the people who will watch the series
40:56can get closer and better understand these pathologies.
41:00From the actors of the series,
41:02there is a strong desire to help
41:04better understand this pathology,
41:06as Alberto Onofrietti explains,
41:08who plays Andrea in the same fire,
41:10in love with Sophia.
41:12A topic of this kind
41:14that has a strong impact,
41:16according to these statistics,
41:20if we could increase a little,
41:22some percentage point,
41:24the knowledge,
41:26it would already be a good result.
41:28THE BIRDS
41:32During the Christmas holidays,
41:34it is easy to drink a few more bottles of sparkling wine
41:36to stay in joy.
41:38One prerogative is the consumption of ethyl alcohol
41:40and ethanol,
41:42considered the most human.
41:44However, scientists used to study winged creatures,
41:46primates and various mammals in their natural habitat,
41:48know it well.
41:50Between a tree and another,
41:52in the prairie forest, for example,
41:54it can happen to see a bird fly zigzag
41:56or a monkey fly as much as it wants.
41:58There are many anecdotes of wild animals
42:00that behave like drunkards
42:02after eating fermented fruit.
42:04In other words,
42:06they also get tanned
42:08and drinking alcohol among non-human creatures
42:10may not be as rare as previously thought.
42:12It remains to be understood, however,
42:14if they do it deliberately and why.
42:16Although the observed cases are few,
42:18in fact, it is generally assumed
42:20that the non-human consumption of ethanol
42:22is rare and accidental.
42:24There is a review published on the magazine
42:26Trends in Ecology and Evolution
42:28in which the authors argue
42:30that since ethanol is naturally present
42:32in almost all ecosystems,
42:34it is likely that it is regularly consumed
42:36by most animals that eat fruit and nectar.
42:38In fact, it is much more abundant
42:40in the natural world than we thought
42:42and most animals that eat sugared fruit
42:44can expose themselves to a certain level of ethanol.
42:46Ethanol, or ethyl alcohol,
42:48became abundant for the first time
42:50about 100 million years ago
42:52in order to produce nectar and sugar
42:54and fruits that the yeast could ferment.
42:56Today, in tropical environments,
42:58low latitude and humid,
43:00concentrations are higher
43:02than in temperate regions
43:04and production takes place all year round.
43:06More often than not,
43:08fermented fruits naturally reach
43:10only 1-2% of alcohol in volume.
43:12But as the authors in Panama and Central America
43:14point out, concentrations of 10.2%
43:16have been found in too ripe palm fruit.
43:18The fact that animals,
43:20for example, already had genes
43:22that could degrade ethanol
43:24before the yeast began to produce it.
43:26But there is evidence that evolution
43:28has perfected this ability
43:30in mammals and birds
43:32that consume fruit and nectar.
43:34In particular, primates and tupas,
43:36small mammals similar to squirrels,
43:38have adapted to metabolize
43:40ethanol efficiently.
43:42Scientists have therefore tried
43:44to analyze the usefulness
43:46of consuming alcohol for animals.
43:48So what could move them
43:50towards the consumption of ethanol?
43:52It is the opposite of human beings
43:54who want to get intoxicated
43:56but do not really want the calories
43:58that come from alcohol.
44:00From the point of view of a human,
44:02animals, on the other hand,
44:04want the calories,
44:06but not the drunkenness.
44:08It is not clear, therefore,
44:10if ethanol is intentionally consumed
44:12as such and further research
44:14is only necessary to understand
44:16that alcohol and other products
44:18during fermentation could
44:20lead animals to the source of food,
44:22although experts say
44:24it is unlikely that they can
44:26detect ethanol itself.
44:28In addition, alcohol could
44:30also have medicinal benefits.
44:32Fruit flies, for example,
44:34intentionally lay their eggs
44:36in substances containing ethanol
44:38that protect their eggs from parasites
44:40and their larvae increase
44:42the absorption of ethanol
44:44This is a kind of relaxation
44:46that could have benefits
44:48in terms of sociality,
44:50observes the behavioral ecologist
44:52first author of the study
44:54Anna Bouland,
44:56from the University of Exeter.
44:58A kind of happy hour effect
45:00deliberately sought by animals
45:02with a specific purpose?
45:04There are still many unanswered questions.
45:06In a future research,
45:08the team plans to investigate
45:10the behavioral and social implications
45:12Finally, we wish everyone,
45:14human beings and animals,
45:16Happy Holidays!
45:20This was our last news,
45:22to contact us you can write to
45:24SaluteChiocciola
45:26at dncronos.com
45:28Thank you for following us
45:30and Merry Christmas to all!
45:42Merry Christmas!