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00:00Number one
00:02A-show
00:05Start is the G
00:08Come on up she sold hold of an charisma
00:11Konkai私が取材したのはがん研究の最前線
00:15日本人のおよそ4人に1人ががんでなくなる中
00:19IPS 細胞を使った治療の研究が進んでいます
00:22今夜はスタジオにその ips 細胞の生みの親山中信也先生にお越しいただいています
00:28最新のプロジェクトとともに後ほど解説をしていただきます
00:37この放送はご覧のスポンサーの提供でお送りします
00:43母本当に紫色が好きでした
00:49綺麗なスカーフ装着でこういうのもいいんだなすごく綺麗な紫色だね
00:54に何か母の喜ぶことをしたいと思った
00:59紫色のスカーフを身につけていただくのはいかがでしょう
01:04ですね 葬儀のご相談は
01:12生きる喜びを試し目よ
01:17そして特等席から眺めてみよう
01:20いいいい 道はその先へ続いている
01:29いいいい
01:32いつまでも人生楽しむために
01:38いつまでも科学は得るだ当総
01:42医療保険はこのままでいいのでしょうかお客様は足りない不安も払いすぎの懸念もぬぐいき
01:48But what should we do?
01:50Therefore, we propose a new form of medical insurance that is just right for everyone,
01:55which integrates monthly insurance and services for self-loading every month.
01:59This is a challenge that can be done because it is Aflac.
02:02President, what is your decision?
02:05Aflac.
02:06A new reason is born that is safe.
02:09Now, let's go.
02:18Vanquisher
02:29Tonight's guest is Mr. Shinya Yamanaka, a Nobel Prize winner,
02:34and Mr. Ryogo Matsumaru, who has appeared for the first time in a long time.
02:37Nice to meet you.
02:39I heard that Mr. Yamanaka's hobby is running.
02:43Actually, I heard that you have just finished the competition of the full marathon.
02:48Are you okay?
02:49Yes, I participated in the Tsukuba Marathon.
02:53I was blessed by the weather and the course, and I was able to run for three and a half hours.
02:58I think it's a good record.
03:00Today, I would like to ask Mr. Yamanaka a lot about the latest projects of IPS cells.
03:08First of all, from here.
03:11People who failed to invest.
03:13People who have fallen in favor in a relationship between men and women.
03:17This is an investigation item carried out by the Chinese Ministry of Tourism and Tourism.
03:23The local government is looking for residents who are dissatisfied with their lives,
03:30and is trying to manage them before they cause an incident.
03:36The trigger was the incident of racial discrimination in China.
03:42Why is the incident now?
03:46When I interviewed people in China, I could see the reason.
03:53Thursday.
03:54The suspect went to the scene of the incident of racial discrimination.
03:59What I saw was...
04:02This is still closed.
04:05Before the incident, it was crowded with citizens, but now I can't see anyone at all.
04:14Two weeks ago at this sports facility.
04:24A car went berserk.
04:26A car went berserk.
04:2835 people were killed one after another, including joggers.
04:37The incident changed the situation in the city.
04:40When I drove around the nearby park...
04:45There are guards at all entrances.
04:49And they're wearing suspenders and bulletproof vests.
04:55It's a very strict security system.
05:00The number of guards increased after the incident has caught the eye of many.
05:06Furthermore...
05:09Right now, a car stop is being set up in response to the incident.
05:16Measures have been taken by the riot police to protect the citizens.
05:22The incident of racial discrimination in China.
05:28In September, in Shenzhen, Guangdong Province...
05:31A man with a knife attacked and killed a 10-year-old Japanese boy.
05:38On Tuesday, a car went berserk in front of an elementary school in Kunan Province.
05:44More than 10 people were injured.
05:48This is a new video that captures the moment when the incident was posted on social media.
05:56It's morning school time.
05:58The children gather to go to the school building on the right side of the screen.
06:04Then...
06:07A car rushed in at full speed.
06:12There is no sign of slowing down.
06:15You can't see the car at all.
06:17As it jumped one after another...
06:22Towards the school building.
06:25Then it changed direction and rushed into the school building again.
06:33The 39-year-old man was driving.
06:36He didn't die, but he shocked society.
06:41When I go to a place where there are a lot of people, I get nervous.
06:46I'm afraid the same thing will happen again.
06:52China, where more than 100,000 Japanese live.
06:57What's behind all these incidents?
07:04It's not a good idea.
07:06I've been thinking about it.
07:08If I'm driven any further...
07:12What will happen?
07:19What did you do before?
07:21It's my first time in an office.
07:22I used to work at a convenience store and a bakery.
07:24I used to work at a cafe and a beauty salon.
07:26I used to work at a pharmacy and a hospital.
07:28Let's all work together and make it a good office.
07:31I have experience.
07:33Office, office, office, office, office...
07:42There is an echo that you use the building over and over again.
07:51This year's last!
07:52If you register a Rakuten card, you get 10,000 points!
07:55Wait a minute!
07:57If you have a Rakuten card, you can get 20,000 points by registering Rakuten Mobile!
08:01Search for Rakuten Card until 10 a.m. tomorrow!
08:04Elixir and...
08:05First, 7 days.
08:08Trolley.
08:09Mochiri?
08:1040 years of collagen science.
08:12Starting today, you too.
08:14Elixir, a lotion for aging care that moisturizes your teeth.
08:19Kind modern Cronos.
08:212nd, Keisei Sanetsu.
08:23Attention!
08:25It's easy to understand.
08:26So?
08:27Reduce fresh water.
08:29Hurry up and finish it.
08:31Kind modern Cronos.
08:35The wind is strong.
08:40Welcome back!
08:41I'm back.
08:45Hokkaido is a feast.
08:47House Hokkaido Fish.
08:50Shionugi RD.
08:51From Rinderon VS.
08:52Premium appearance!
08:54Premium prescription with skin recovery ingredients and sterilizing ingredients in strong steroid.
08:59This symptom will be cured.
09:01Rinderon VS. Premium.
09:03Ping-pong!
09:04To my sensitive skin.
09:06D-PROGRAM high-performance foundation lotion.
09:08The season of dryness is...
09:09Dry, dry.
09:10Gensen moisturizing ingredients for sensitive skin.
09:14Deep moisture lasts a long time.
09:17To smooth skin.
09:21Waxer.
09:24China, where racial discrimination is rampant.
09:30This is a video posted on SNS by the police on the 13th of this month.
09:37The title is...
09:38What if a car rushes into a child?
09:42Watch how I move.
09:44Look at the timing and quickly run behind the car.
09:49Now, when I give the signal, run and run away.
09:52Listen carefully to the signal.
09:55Run away!
10:00I don't know if it's effective,
10:02but I was lecturing on how to protect yourself from a car rush.
10:08Also, this is a technique posted on SNS by the police on the 13th of this month.
10:16Throw what you have into the car that rushes in and cover your eyes.
10:20For example, clothes, eggs, flour.
10:25This post has been read more than 100,000 times.
10:36A series of cases of racial discrimination in China.
10:42Why are there so many cases of racial discrimination in China?
10:48What's going on?
10:51Experts say...
10:53I think the influence of SNS is great.
10:57For example, if someone uses a car and suddenly runs into a car,
11:02I'm dissatisfied, so I'll do this.
11:06This increases the power of transmission and spread.
11:12The President of the People's Republic of China, Xi Jinping,
11:15took the lead in dealing with the protests.
11:18He gave instructions to the local government to take proper measures.
11:26The government of Kanton responded to me as soon as possible.
11:30People who lost their jobs among the residents,
11:33people who lost their jobs due to the relationship between men and women,
11:36They found people who fit the eight types of people.
11:39It is said that the government has taken measures to strengthen management.
11:45By monitoring people who are dissatisfied,
11:48This measure to keep an eye on crime.
11:51How are you looking for people of the eight types?
11:56Ban Ki-sha interviews the citizens of Kanton.
12:00Do you know how to find people who have lost their jobs or are in a bad relationship to prevent the reoccurrence of the incident?
12:12That's what's going on.
12:15Do you visit each and every house?
12:18I don't know the details because the residents' committee is doing it.
12:24So, to the office of the residents' committee.
12:27The residents' committee is an organization of local residents who manage the citizens under the guidance of the government.
12:36Are you looking for people who are at risk of crime here?
12:42Is there anything?
12:45I want to make sure.
12:47I'm doing it.
12:49Are you looking for people at risk because of the incident?
12:54Is it because of the incident?
12:57I've been doing it since I usually do it.
13:00I've been strengthening it recently.
13:03After the incident,
13:05In fact, the residents' committee staff came to the house to investigate.
13:13Are you in trouble?
13:16I was asked if I needed the help of the government.
13:20You're asking people who are in a bad financial situation.
13:24A new security measure that can be said to be the government of the people.
13:30The experts point out that this kind of greedy policy is what builds up people's dissatisfaction and leads them to the incident.
13:41In fact, the lockdown has had a great impact.
13:44Lockdown is actually a confinement.
13:47Everyone is so mentally damaged that only those who have experienced it will understand.
13:52Another thing is the economy.
13:55I can't do business because of the lockdown.
13:58I thought the economy would get better after the lockdown, but it didn't.
14:03That's why everyone is even more dissatisfied.
14:06It's very pessimistic.
14:08I think this is the situation.
14:11What is the reality of the Chinese economy?
14:15When I ran in Beijing two days ago,
14:19It's a lot.
14:22There are a lot of crossroads.
14:26The workers were looking for a job that day.
14:33They read the two-dimensional code written by the Japanese government and apply for a job.
14:41This person is also looking for a job.
14:47I can't find a job in three consecutive days.
14:51I have a wife and two children.
14:55The children go to school and spend more than 10,000 yuan a year.
15:00I have to make money.
15:03The school fee is stupid.
15:05The daily meals are not enough.
15:10It's not a good idea.
15:13If I'm pushed any further,
15:17I have no choice but to take things away.
15:20There are people over there who sell cell phone numbers and blood.
15:28Cell phone numbers are 400 yuan.
15:31Blood is 800 yuan.
15:36How many days can I live with that?
15:41The employment difficulties of young people are also getting worse.
15:45He is 21 years old and has just graduated from university.
15:50I couldn't get a job easily.
15:53The educational background required now is very high.
15:58He studied computer science at university,
16:02but he couldn't find a job.
16:05He makes a living by working part-time at a food delivery company.
16:12I'm worried about my future.
16:15What should I do in the future?
16:19Do you have any concerns?
16:23No, I don't.
16:26I have no choice but to solve my stress by myself.
16:33Mr. Matsumura, how do you perceive the situation in China?
16:38When I read the news,
16:41I think there are many people who don't perceive it as Chinese news.
16:47I wonder if there is a possibility that the same thing will happen in Japan.
16:53Recently, I've been hearing a lot about the dark side of the news.
16:57Young people, especially those who are poor,
17:01aim for people who don't have a community to talk to.
17:05They can't talk to anyone,
17:08but they have to do it to save their lives.
17:13I think the whole country is worried about the future.
17:18I think it's time for Japan to learn what measures it can take as a country.
17:26Mr. Yamanaka, how do you perceive the situation in China?
17:32In the world of research,
17:35we are seeing great results from Chinese researchers.
17:40In the past, it was the results of Chinese researchers in the United States and Western countries.
17:46Now, the results of Chinese researchers working hard in China
17:50are coming out one after another.
17:53I think there is a big difference between the current situation
17:58and the situation in the United States.
18:02I can't help but feel that the situation is getting worse.
18:07President Trump in the U.S. is in a position to deal with China strictly.
18:13Depending on the policy, it may affect China's economy.
18:28What is a children's canteen?
18:41What is a children's canteen?
18:44There are a lot of people.
18:46There are adults, too.
18:48Hello.
18:50May I sit here?
18:52Do you come here often?
18:53Yes.
18:55It's not just for children.
18:57It's not just a place to eat.
18:59It's a place for everyone.
19:01A children's canteen is a children's canteen.
19:04Musubie, a support center for children's canteens nationwide.
19:07AC Japan supports this activity.
19:10Everyone has their own worries.
19:14I can't eat too much after drinking.
19:17It's still painful to eat late at night.
19:20Greed, sweets, love, and feelings.
19:25In such a case, we use anti-aging agents.
19:29Four digestive agents are used for various ailments.
19:32It works well for sweet potatoes.
19:34In other words,
19:38If you feel pain, you should eat early.
19:41Although it is a literary management job,
19:44I can make a revolutionary business application.
19:47It looks fun.
19:49You laugh with that face.
19:52Let's make a business application with no code.
19:57I can't even use this app on my smartphone.
20:00It's good. It's like reaching a itchy place.
20:02Someone who is very troublesome is making this.
20:05Who is it?
20:07Let's make a business application with no code.
20:11Today, we will go to a new spot in the neighboring town.
20:13I'm sorry to ask you to go with me.
20:15I wanted to take a picture, too.
20:17There are many curves on this road.
20:19What is that switch?
20:21Spacia automatically slows down.
20:23It runs smoothly in the middle of the lane.
20:25It has evolved so far.
20:27I think it's good.
20:30I'm hungry.
20:32I'm scared.
20:34It's okay if you keep the middle of the lane.
20:36It's like Spacia.
20:37Spacia continues to accelerate on the road.
20:44This is the news that set a great record.
20:48Ohtani Shouhei of DOGERS won the MVP for the third time in a row for two consecutive years.
20:57This season showed unprecedented activity.
21:00In fact, when I analyzed the announcement of the MVP this time, I was wondering why the person who had confirmed the winner before the announcement.
21:13Today, Tokyo Ginza.
21:19Ohtani Shouhei, congratulations on winning the MVP.
21:24MVP commemorative sale has been held at an antenna shop in Iwate Prefecture, the hometown of Ohtani Shouhei.
21:34According to the number, some of the products are 17% off.
21:40Many people were visiting.
21:42He has two bags.
21:45It's heavy.
21:47I thought this weight was part of the weight of Ohtani Shouhei's business.
21:56A sports shop in Shibuya, Tokyo, has been holding an event to commemorate the MVP award since yesterday.
22:04He's taking a video.
22:07He's taking a lot of pictures.
22:10At the end of the line of sight, the ball in the case is actually...
22:19The ball when Ohtani Shouhei achieved the 51st home run.
22:26The auction price was about 65 million yen.
22:33I was so happy that the ball was here for a moment in that century.
22:41There is no precedent that a DH player who focuses only on hitting and not on defense has won the MVP.
22:51While the world is watching, Ohtani Shouhei won the MVP for the third time in a row.
22:58It was decided by a vote of 30 reporters, but it was a unanimous vote from all of them.
23:07The last reporter verified the video at the time of the announcement.
23:11Then, there was a scene where Ohtani Shouhei's win was known even before the announcement.
23:19Everyone saw that video and thought that the judge and Ohtani would win.
23:28The MVP of the All-American Baseball Journalist Association
23:34At 6 p.m. on Thursday, the All-American Baseball Journalist Association announces the MVP of the All-American Baseball Journalist Association every year.
23:46There were three finalists in the league.
23:50First of all, the last reporter paid attention to the beginning of the program.
23:58In the opening video, there is a place like a stadium train station made of CG.
24:15Time has passed.
24:17At night.
24:23The moment the door closes.
24:25The first thing that was shown was a video of Ohtani Shouhei.
24:31In addition, if you pay attention to the presenter who announces the MVP,
24:36the presenter is the same as Ohtani Shouhei.
24:40He is the head coach of the Dodgers.
24:55I didn't hear that.
25:00Some people were convinced that Ohtani Shouhei would win before the announcement of the MVP of the All-American Baseball Journalist Association.
25:07In addition, if you look at the program,
25:10just before the MVP announcement at 6 p.m.,
25:14a program called Ohtani 50-50 was broadcasted at 4 p.m.
25:18It was a digest of the match that achieved 50-50.
25:26In the SNS, it was pointed out that it was too bright.
25:33When did the reporter who voted for Ohtani Shouhei know the results?
25:40The person who voted is prohibited from talking about the contents until the results are announced.
25:48It is a secret until the results are announced.
25:52In fact, the MVP is subject to the results of the regular season.
25:57Voting was closed more than a month before the playoff.
26:03Another reporter said that he was already convinced that Ohtani Shouhei would win at this point.
26:10It was an easy choice.
26:13Sometimes I'll talk to the providers and they'll use quota.
26:17But this time, I thought everyone would vote for Ohtani.
26:23Ohtani Shouhei won the MVP for the first time in history.
26:29Next season, he is expected to win the Cy Young Award, which will be given to the most active player.
26:39How about Cy Young Award and MVP next year?
26:43It would be great if I could win the Cy Young Award.
26:47First of all, I want to come back and show a stronger performance.
26:55My goal is to go up to the mound with confidence.
26:58After the surgery on his right leg in September last year,
27:03he continued to rehabilitate himself and gradually threw stronger balls.
27:08In August, he recovered with a bullpen until he practiced throwing balls.
27:13It seemed to be going well, but...
27:25When he made his debut in the World Series, he had surgery on his left shoulder.
27:30Now that the surgery is over, he has just started training his body.
27:36Will he be able to throw until his debut?
27:43The reporter in charge of the Major League...
27:47There is a 90% chance that he will be able to throw at his debut.
27:52Ohtani knows his body very well.
27:56He is a very intelligent athlete.
28:01On the other hand, this reporter...
28:06I think the possibility is low.
28:09Less than 5%, maybe 2-3%.
28:14He pointed out that his training was delayed due to shoulder surgery.
28:20I think he will be able to throw from late April to May.
28:2690% and 5%.
28:29The two reporters are expecting both extremes.
28:33Former Major League player Ryota Igarashi...
28:38The burden will be greater here.
28:41This is called a miracle part, and it improves movement 100 times.
28:47Even as an adult, Nikkun is chasing the same dream.
28:51This part is very small.
28:54It has never been used before, so it is very powerful.
28:59It moves very smoothly.
29:04It changes the world very quickly.
29:09Mitsumi Minebea
29:12Last winter, there were 54 million people who felt that they could not live well.
29:17I protect my health with immune care.
29:22Right now, plasma lactobacillus is active in the immune system.
29:27It reacts to external stimuli and works for your health.
29:33Kirin's immune care
29:37It is an invention to protect your health.
29:41The line of sight is cold.
29:44It's good, right?
29:46It's cold.
29:48It's cold.
29:50It's warm.
29:52It's warm.
29:56Kotatsu in Nitori
29:58Adjust the height according to the sofa.
30:05It can be used all year round.
30:08Nitori
30:11Hello, new idea.
30:13N-BOX JOY, debut.
30:16I want to expand the enjoyment of the car.
30:19Honda puts the car tank in the center.
30:24Using this unique technology, it creates a comfortable space that is as wide as a terrace.
30:33Where do you enjoy this new space?
30:37N-BOX JOY, debut.
30:41Sorry to keep you waiting.
30:43I made a phone call.
30:45Did you go?
30:47I think I went.
30:49It's ArtNature's experience.
30:52It's good for your hair.
30:55It's fast.
30:57It changes a lot.
31:02It's cold.
31:04It's ArtNature's experience.
31:06N-BOX JOY, debut.
31:15Ohtani, who had surgery on his left shoulder.
31:20Will he be able to play as a starter until the opening?
31:25Mr. Igarashi, who was a starter in the former Major League.
31:28Ohtani, who was a starter in the former Major League.
31:31As a starter pitcher,
31:35the possibility of throwing
31:38is 35%.
31:4035%.
31:42It's low.
31:44To be honest, I'm a starter in Japan,
31:48but I don't think I have to do it to make it here.
31:53Even in the case of a right throw,
31:56it is said that the injury of the left shoulder will affect it.
32:00After throwing,
32:03the arm pulls back with a rebound.
32:06It's pulled back.
32:08I think this is the biggest burden on the shoulder.
32:11Let's take a look at the video of last year,
32:15when he was a starter.
32:22Certainly, the left shoulder was raised high by the rebound he threw.
32:29I think this is where the pain occurs.
32:34I think it will come while checking what kind of burden there is in the movement.
32:39I think it will take a little longer to throw the ball from here.
32:44Mr. Ohtani betrays me in a good way,
32:47so I want to look forward to that.
32:49Mr. Yamanaka, who also likes sports,
32:52Did you pay attention to Mr. Ohtani's game?
32:55I go to San Francisco every month,
32:58so Mr. Ohtani comes several times a year.
33:01There is a place where you can jump into the sea.
33:05That's my jogging route.
33:08I was wondering if he would come on the way of jogging.
33:11I was watching it this year, but it was a little further.
33:14How far did you go?
33:16I went to the top of the building.
33:19He didn't come all the way here.
33:22But his activities are a great courage for us Japanese.
33:27I hope he will recover from his injury next year.
33:32Is it a big influence on the whole of Japan?
33:35It's big.
33:37He is the best baseball player in the world.
33:40There are few people who are the best in the world in Japan.
33:45Especially for young people,
33:47there are many people who don't know the good times in Japan.
33:51I think Mr. Ohtani is showing us that now.
33:55Mr. Matsumaru, you are in your early years.
33:58How do you feel?
34:00I'm under a lot of pressure because I'm in my early years.
34:03But when I see Mr. Ohtani, who is the same age as me,
34:06and Mr. Matsumaru, who is the same age as me,
34:09we are getting closer to our 30s.
34:12It's time to give up our dreams and start thinking about reality.
34:16I think we can still do it.
34:19I respect him as a person who raises the morale of the whole of Japan.
34:24Is it a little pressure to be called Mr. Ohtani?
34:26That's right.
34:28Everyone is like that.
34:30Next.
34:32We will now report on the weather in Japan.
34:35Tomorrow will be a sunny day with a lot of high pressure.
34:39The weather on the Japanese coast will also recover gradually,
34:42and the cold in Sapporo and Niigata will loosen.
34:45This is the weather forecast for the west of Japan and Okinawa.
34:48There will be a lot of rain the day after tomorrow,
34:51and after that, cold rain will continue on the Japanese coast.
34:54On the other hand, the Pacific side will be sunny,
34:57but you will feel the progress of the season.
34:58This is the weather forecast for the north of Japan and the east of Japan.
35:01The weather will be downhill from Tuesday to Wednesday,
35:04and it will rain in various places.
35:06In the second half of the week,
35:08there will be winter-type high pressure,
35:10and cold rain and snow will continue in the north of Japan and the north of Japan.
35:13The Pacific side will be sunny.
35:18We will now report on the news.
35:20The South Korean government said that North Korea
35:23is planning to launch additional military police satellites
35:25by the end of this year.
35:28North Korea launched its first military police satellite in November last year,
35:32and Kim Jong-un has shown a policy
35:35to launch three additional satellites by the end of this year.
35:38In May of this year, it failed to launch,
35:41and the date of the launch has not been confirmed since then.
35:44In this situation,
35:46the North Korean government is planning to launch three additional satellites
35:49by the end of this year.
35:51The date of the launch has not been confirmed.
35:54In this situation,
35:56the South Korean government has shown a policy
35:59to launch three additional satellites by the end of this year.
36:02In addition,
36:04the North Korean government has shown a policy
36:07to launch three additional satellites by the end of this year.
36:10The North Korean government has shown a policy
36:13to launch three additional satellites by the end of this year.
36:16Before the glory of Mikasa no Miyahi Yuriko
36:18and eyes of her former subjects gorgeous appearance,
36:21thelight of the Tendo Kingdom hunted down.
36:23It was around 2 PM today
36:26that the farewell ceremony
36:29was held held
36:31at Mikasa no Miya
36:34where her hair and vegetables
36:37were tied up one after another.
36:40The closing ceremony
36:42was hosted
36:44by her later rebellious form,
36:46After that, His Majesty the Emperor and his wife visited the Mikasono-Miya temple to pay their respects.
36:57Tonight and tomorrow night, there will be a funeral service for the deceased.
37:05Will this be a new light for cancer treatment?
37:08Dr. Yamanaka will explain the latest IPS research.
37:14Life Net Life.
37:16It's good to live as you like when you're young.
37:19But money is important.
37:21That's why you shouldn't take too much insurance.
37:24Life Net Life.
37:25It's good.
37:26I wish I had it when I was young.
37:29New medical insurance.
37:30Do you know?
37:31New medical insurance?
37:32Yes.
37:33We want to keep medical insurance.
37:35But we want to make medical insurance cheaper.
37:37Medical insurance for us who are greedy.
37:39This is all my medical insurance.
37:42Life Net Life.
37:45NX Nippon Express.
38:07We have samurai spirit.
38:11Life Net Life.
38:15To do what I want to do, I drink less alcohol.
38:21I want to enjoy myself as much as I can.
38:25I want to stay in the moment.
38:28That's why I use this dry.
38:303.5% alcohol, super dry.
38:33It's sharpened and transparent.
38:373.5%, right?
38:40Super dry.
38:42Crystal.
38:48No matter how beautiful the castle is,
38:50if someone doesn't protect it,
38:52it will disappear into the darkness of history.
38:56For centuries,
38:58many people have protected the castle.
39:01Just like those nameless people,
39:04Nippon Kanzai respects each and every building
39:08and continues to maintain its value.
39:12Nippon Kanzai.
39:16Isn't a truck cool?
39:18What is it?
39:19It looks like a free vehicle.
39:22I want a car.
39:24You can buy a truck with your smartphone.
39:26Yeah.
39:27Can you drive it with a normal license?
39:29No.
39:30You said you wanted one.
39:32That person is cool.
39:34No.
39:37What is it?
39:39You can drive it with a normal license.
39:41Anyone can drive a truck.
39:44This program was brought to you by these sponsors.
40:01Now, let's hear from Mr. Shinya Yamanaka.
40:05Today, he will tell us about two new projects using iPS cells.
40:12Thank you for having me.
40:15First of all, what is an iPS cell?
40:18It is an all-purpose cell that is made from the cells of the skin and blood
40:22and can change into various cells of the body.
40:26As you know, Mr. Yamanaka, the father of iPS,
40:29was awarded the Nobel Prize in Psychology and Medicine in 2012.
40:34Let's see what kind of disease he is trying to cure with this iPS cell.
40:41Please come closer.
40:43I put a list on the board.
40:47There are a lot.
40:48Yes.
40:49Let's look at it from the top.
40:50For example, Parkinson's disease,
40:52and heavy heart failure,
40:55or damage to the spinal cord,
40:58and some cancers that are still difficult to treat with antibiotics.
41:03In fact, these have already started to show the effect on patients
41:06with clinical trials and so on.
41:10Mr. Yamanaka, this is just a part of it,
41:12but are you doing a lot of research to make it practical?
41:15Yes, I'm working with a lot of researchers and companies
41:19to develop treatments for many diseases and injuries
41:23from the head to the feet and the whole body.
41:27Mr. Matsumura, is there anything you are interested in?
41:29I have the impression that the heart and brain seem to be difficult,
41:33but is there anything particularly difficult about this cell?
41:36Basically, any cell can do it.
41:40However, in many cases, it is not possible to do it
41:45until it is exactly the same as the cells in the body.
41:48That's where each researcher's specialty lies.
41:52I'm still doing my best to research.
41:55I see.
41:56In this case, I think the ovarian cell cancer is a woman's specialty.
42:01Yes, that's right.
42:02For example, have you started research on breast cancer and uterine cancer?
42:05Yes, I'm working on a research project to develop a immune cell
42:10that can fight cancer against various cancers from the iPS cells.
42:16I'm doing this with a lot of momentum,
42:18not just in Japan, but all over the world.
42:21We just heard the story,
42:23but here is the first of the latest projects we heard from Dr. Yamanaka today.
42:27A cancer that occupies about one-fourth of the Japanese population.
42:31Is there a new light in the treatment?
42:34There is something in the cancer that is difficult to treat,
42:36and a new treatment method is expected.
42:39This time, I specially interviewed him
42:43to study how to apply the iPS cells to it.
42:47Nice to meet you.
42:49Nice to meet you.
42:52Nice to meet you.
42:54This time, we will be guided by Dr. Kaneko,
42:57the top runner of cancer treatment research using iPS cells.
43:03Where did he go?
43:07This is the biopsy room.
43:10This is a little scary, isn't it?
43:12There is something that makes me nervous.
43:15A new cancer treatment research is being carried out ahead of this.
43:22Dr. Kaneko's guidance
43:24is to wipe the equipment such as cameras with a disinfectant sheet before entering the room,
43:29put on gloves and masks, and finally go inside.
43:36What did Masu see there?
43:41There are immune cells that fight against cancer in this.
43:45There are actual cells.
43:52Excuse me.
43:53I can't see it in my eyes, but there are a lot of cells in this orange liquid.
43:59These are cells called T-lymphocytes.
44:04If you look at this liquid with an electron microscope,
44:10the black part is a lump of T-cells made from iPS cells.
44:17This is a cell that fights against cancer and external enemies.
44:24This is a video of T-cells actually fighting against cancer cells.
44:29A black T-cell is attacking a green cancer cell.
44:36Then one of the cancer cells is defeated by the T-cell and becomes black.
44:41At the same time, the T-cell loses its power and weakens.
44:46Dr. Kaneko's research is to revive this weakened T-cell.
44:53First, the patient himself takes out the T-cell that fights against the cancer cell.
44:59After the fight, the T-cell is weak.
45:05By adding a hand to this and turning it into an iPS cell, the T-cell is revived.
45:11After that, the T-cell is transformed into a T-cell again.
45:18A large number of T-cells that have been reborn are returned to the patient and fight against the cancer cell.
45:28This is a T-cell that regains its original power.
45:33You can see that the T-cell is defeated one by one.
45:45The difference is obvious.
45:48The T-cell is a cancer cell.
45:51The T-cell is a cancer cell.
45:54The T-cell is a cancer cell.
45:57You said that cancer treatment is using anti-cancer drugs and radiation therapy.
46:03What is the difference between those two?
46:05The treatment of radiation therapy and anti-cancer drugs is called the three pillars.
46:10The treatment of the immune system is the fourth pillar.
46:15iPS cells have a strong image of regenerative medicine.
46:19How do you use and apply them?
46:22I've been getting a lot of attention in the last 10 years.
46:26Did you imagine how to apply it when you discovered the iPS cell?
46:32I announced the iPS cell in 2007.
46:35At that time, the immune therapy was not so popular among scientists.
46:43Dr. Honjo's drug called Opzivo was introduced.
46:48The immune therapy was called the fourth treatment.
46:52Researchers like Dr. Kaneko, who tried to use the iPS cell for cancer treatment,
46:59were all over the world.
47:01It's a great competition.
47:03Dr. Kaneko is one of the top researchers in the world.
47:06Mr. Matsumura, how was it?
47:08I lost my mother to breast cancer more than 10 years ago.
47:12The treatment at that time was the three pillars.
47:16If there was an iPS treatment, my mother's life might have been saved.
47:21What do you need to deliver it to people who are suffering from cancer?
47:29It's not just about iPS cells.
47:32There is a possibility that the immune therapy can cure cancer that has never been cured before.
47:37In the last 5 to 10 years, there have been many cancer treatments that have not been cured.
47:45I think that the time has come.
47:51I don't know the exact date yet.
47:54I'm aiming for 5 to 10 years from now.
47:57I'm doing my best for each company.
48:01What about the treatment cost?
48:04This is a big problem.
48:06If you leave it alone, the cost of treatment will increase.
48:09I'm trying to reduce the cost of treatment and make it accessible to everyone.
48:15I'm doing a lot of things.
48:17One of them is the iPS Foundation that we created 5 years ago.
48:21It aims to provide treatment-appropriate iPS cells at a reasonable price to companies as much as possible.
48:29There was also a question of cost, not just technology.
48:32In fact, the latest research is underway to make it easier for anyone to receive iPS treatment.
48:37That's the second theme.
48:39Treatment is your own iPS.
48:42What is MyiPS?
48:45In the first place, most of the iPS cells transplanted to patients are made from donor cells, not the patient himself.
48:53However, in this case, one of the challenges is that it is not your own cell, so there is a possibility that rejection will occur.
49:01And if you try to make your own cell, it will take half a year and 50 million yen to make an iPS cell.
49:11The MyiPS project is currently under development to solve these two problems at the same time.
49:21What does this mean?
49:23Almost all of the clinical trials we are conducting now are conducted using iPS cells made by donors provided by our foundation.
49:33However, there is a possibility that rejection will occur depending on the condition of the patient and the location of the transplant.
49:40In the case of MyiPS, the patient's own blood is drawn, and then the iPS cell is made using an automatic biopsy device.
49:53Five years ago, it took about half a year and 50 million yen to make an iPS cell.
50:03Now, with this new method, it costs about 1 million yen, and it takes about a month to make each patient's own iPS cell.
50:13This kind of project is getting closer to completion.
50:17Mr. Matsumura, how about MyiPS?
50:19I want to do it.
50:21If it costs 1 million yen in a month, it will be realistic as a surgery fee or treatment.
50:26That's right.
50:28Depending on the condition of the patient and the type of disease, there are many cases where the existing iPS cells are sufficient.
50:34However, depending on the type of disease, such as a special type of immunity, MyiPS may be the best choice.
50:41For those people, we are thinking of providing our own iPS cells at a reasonable price.
50:47So, if this biopsy device is made, anyone can receive the treatment of iPS cells?
50:53Yes.
50:55If you need your own iPS cells, you can make them with this device.
51:00If you don't need them, you can make them with what you already have.
51:05If you make them with what you already have, you can reduce the price.
51:11It's a case-by-case process.
51:13The mission of the iPS Foundation is to provide the best iPS cells to any patient in Japan at a reasonable price.
51:22I think it's a good idea.
51:24However, I'm worried about the safety of the new device.
51:32As you said, any chemical technology has both advantages and disadvantages.
51:40The important thing is transparency.
51:43It's very difficult to tell the general public about our research activities accurately and easily.
51:53It's not easy for researchers to do that.
51:56So, it's very important to have a science communicator in between.
52:02Mr. Matsu is also a scientist.
52:06From now on, it's very important to connect scientists with the general public.
52:13Of course, scientists are the ones who make the latest technology.
52:17How do you make it?
52:19It's the same as what you're seeing on TV right now.
52:21It's the same as what you're seeing on TV right now.
52:24We are professional researchers, but we are not professional communicators.
52:29It's a different job, so we need a different professional.
52:35Mr. Matsumaru, how was it to hear the story of the Nobel Prize winner today?
52:40I thought it was interesting that the story of the future was coming soon.
52:46Above all, I think it's very important to have the right understanding of the world
52:51so that this technology can be delivered to those who need it as soon as possible.
52:58I think we're in a world where a lot of information is popping up,
53:03so I think it's very important for everyone to be able to think that it's good
53:08to properly identify the wrong information and the correct information.
53:14I think it's also the media's responsibility.
53:16Mr. Ushio, your imagination is expanding.
53:19It may be a bit of a leap, but do you think life expectancy will continue to grow?
53:25I think life expectancy will continue to grow to some extent.
53:27According to researchers, I saw it in today's newspaper,
53:31there are people who think they will live to be 500 years old,
53:36but we think that's quite difficult.
53:39But it's not about life expectancy, it's about health and well-being.
53:43You can do what you want to do on your own without care or nursing.
53:47You can run on your own, you can go shopping on your own.
53:50Our goal is to extend that health and well-being.
53:54We look forward to your research in the future.
53:56Thank you, Mr. Ushio.
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